This gene encodes a member of the phosphoinositide phospholipase C beta enzyme family that catalyze the production of the secondary messengers diacylglycerol and inositol 1,4,5-triphosphate from phosphatidylinositol in G-protein-linked receptor-mediated signal transduction. Alternative splicing results in multiple transcript variants.,PLCB3,Cancer,Signal Transduction,G protein signaling,G2/M DNA Damage Checkpoint,Phospholipase Signaling Pathway,ErbB-HER Signaling Pathway,Cell Biology & Developmental Biology,Cytoskeleton,Actins,Endocrine & Metabolism,Lipid Metabolism,AMPK Signaling Pathway,Neuroscience,Neurodegenerative Diseases,PLCB3