FASL
(Fas Ligand (TNF Superfamily, Member 6) (FASL))
适用
小鼠, 大鼠
宿主
仓鼠
克隆类型
单克隆
标记
This FASL antibody is conjugated to FITC
应用范围
Flow Cytometry (FACS)
特异性
Recognizes both Mouse and Rat CD178. Clone MFL4 is reported to block CD178/CD95 induced apoptosis. We recommend the use of AM20860LE-N for functional studies.
Optimal working dilution should be determined by the investigator.
限制
仅限研究用
浓度
0.1 mg/mL
缓冲液
PBS containing 0.09 % Sodium Azide as preservative and 1 % BSA as stabilizer
储存液
Sodium azide
注意事项
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项
Avoid repeated freezing and thawing.
储存条件
4 °C/-20 °C
储存方法
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. This product is photosensitive and should be protected from light.
抗原
FASL
(Fas Ligand (TNF Superfamily, Member 6) (FASL))
CD178, otherwise known as Fas Ligand/ CD95L, a 40 kDa type II transmembrane glycoprotein and member of the TNF/NGF superfamily, expressed by activated T cells and NK cells, which can be induced on a variety of cells by radiation, heat shock, chemotherapeutic agents and viral infection. CD178 acts as a key effector of cytotoxicity and in the regulation of immune responses. The binding of CD178 to its receptor CD95 (Fas), induces Fas-mediated apoptosis of target cells, and may be involved in the induction of peripheral tolerance and neutrophil chemotaxis. The binding of decoy receptor 3 (DcR3) to CD178 has been shown to inhibit CD178-mediated apoptosis.Synonyms: APT1LG1, APTL, Apoptosis antigen ligand, CD95L protein, FASL, FASLG, Fas antigen ligand, TNFSF6, Tumor necrosis factor ligand superfamily member 6