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PICALM 抗体 (AA 290-460)

PICALM 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6145606
发货至: 中国
  • 抗原 See all PICALM 抗体
    PICALM (Phosphatidylinositol Binding clathrin Assembly Protein (PICALM))
    抗原表位
    • 15
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 290-460
    适用
    • 24
    • 24
    • 22
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    宿主
    • 35
    • 2
    克隆类型
    • 37
    多克隆
    标记
    • 19
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PICALM antibody is un-conjugated
    应用范围
    • 32
    • 13
    • 13
    • 10
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    序列
    IKDSTAASRA TTLSNAVSSL ASTGLSLTKV DEREKQAALE EEQARLKALK EQRLKELAKK PHTSLTTAAS PVSTSAGGIM TAPAIDIFST PSSSNSTSKL PNDLLDLQQP TFHPSVHPMS TASQVASTWG GFTPSPVAQP HPSAGLNVDF ESVFGNKSTN VIVDSGGFDE L
    交叉反应
    人, 小鼠
    产品特性
    Polyclonal Antibodies
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 290-460 of human PICALM (NP_001008660.1).
    亚型
    IgG
    Top Product
    Discover our top product PICALM Primary Antibody
  • 应用备注
    WB,1:1000 - 1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    PICALM (Phosphatidylinositol Binding clathrin Assembly Protein (PICALM))
    别名
    PICALM (PICALM 产品)
    别名
    LAP-3 antibody, PEPS antibody, CALM antibody, CLTH antibody, LAP antibody, PAP180 antibody, fit-1 antibody, fit1 antibody, mKIAA4114 antibody, Calm antibody, leucine aminopeptidase 3 antibody, phosphatidylinositol binding clathrin assembly protein antibody, si:ch211-200p22.4 antibody, LAP3 antibody, PICALM antibody, Picalm antibody, si:ch211-200p22.4 antibody
    背景
    This gene encodes a clathrin assembly protein, which recruits clathrin and adaptor protein complex 2 (AP2) to cell membranes at sites of coated-pit formation and clathrin-vesicle assembly. The protein may be required to determine the amount of membrane to be recycled, possibly by regulating the size of the clathrin cage. The protein is involved in AP2-dependent clathrin-mediated endocytosis at the neuromuscular junction. A chromosomal translocation t(10,11)(p13,q14) leading to the fusion of this gene and the MLLT10 gene is found in acute lymphoblastic leukemia, acute myeloid leukemia and malignant lymphomas. The polymorphisms of this gene are associated with the risk of Alzheimer disease. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.,PICALM,CALM,CLTH,LAP,Signal Transduction,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,PICALM
    分子量
    59 kDa/66 kDa/68 kDa/70 kDa
    基因ID
    8301
    UniProt
    Q13492
    途径
    Synaptic Membrane
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