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RUNX2 抗体 (AA 251-351)

RUNX2 适用: 人 WB, IF, IHC (p), EIA 宿主: 小鼠 Monoclonal 1D2 unconjugated
产品编号 ABIN614560
发货至: 中国
  • 抗原 See all RUNX2 抗体
    RUNX2 (Runt-Related Transcription Factor 2 (RUNX2))
    抗原表位
    • 16
    • 16
    • 8
    • 7
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 251-351
    适用
    • 115
    • 46
    • 30
    • 10
    • 9
    • 8
    • 8
    • 7
    • 7
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 106
    • 11
    小鼠
    克隆类型
    • 99
    • 18
    单克隆
    标记
    • 59
    • 8
    • 6
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RUNX2 antibody is un-conjugated
    应用范围
    • 91
    • 46
    • 31
    • 25
    • 10
    • 9
    • 8
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    Recognizes Runt-related Transcription Factor 2 (RUNX2).
    交叉反应 (详细)
    Species reactivity (tested):Human.
    纯化方法
    Protein A Chromatography
    免疫原
    Partial Recombinant RUNX2 (NP_004339, 251 a.a. ~ 351 a.a) protein with GST tag.
    克隆位点
    1D2
    亚型
    IgG2a
    Top Product
    Discover our top product RUNX2 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    PBS, pH 7.2
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store the antibody (in aliquots) at -20 °C.
  • 抗原
    RUNX2 (Runt-Related Transcription Factor 2 (RUNX2))
    别名
    RUNX2 (RUNX2 产品)
    背景
    RUNX family members are DNA-binding proteins that regulate the expression of genes involved in cellular differentiation and cell cycle progression. RUNX2 is essential for skeletal mineralization in that it stimulates osteoblast differentiation of mesenchymal stem cells, promotes chondrocyte hypertrophy and contributes to endothelial cell migration and vascular invasion of developing bones. Regulating RUNX2 expression may be a useful therapeutic tool for promoting bone formation. Mutations in the C-terminus of RUNX2 are associated with cleidocranial dysplasia syndrome, an autosomal-dominant skeletal dysplasia syndrome that is characterized by widely patent calvarial sutures, clavicular hypoplasia, supernumerary teeth, and short stature.Synonyms: AML-3, AML3, Acute myeloid leukemia 3 protein, CBFA1, Core-binding factor subunit alpha-1, OSF-2, OSF2, Osteoblast-specific transcription factor 2, PEA2-alpha A, PEBP2-alpha A, PEBP2A, Polyomavirus enhancer-binding protein 2 alpha A subunit, Runt-related transcription factor 2, SL3-3 enhancer factor 1 alpha A subunit, SL3/AKV core-binding factor alpha A subunit
    基因ID
    860
    NCBI登录号
    NP_001015051
    UniProt
    Q13950
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