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RUNX2 抗体 (AA 251-351)

This anti-RUNX2 antibody is a 小鼠 单克隆 antibody detecting RUNX2 in WB, IF, IHC (p) 和 EIA. Suitable for 人.
产品编号 ABIN614560
发货至: 中国

Quick Overview for RUNX2 抗体 (AA 251-351) (ABIN614560)

抗原

See all RUNX2 抗体
RUNX2 (Runt-Related Transcription Factor 2 (RUNX2))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This RUNX2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

克隆位点

1D2
  • 抗原表位

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    AA 251-351

    特异性

    Recognizes Runt-related Transcription Factor 2 (RUNX2).

    交叉反应 (详细)

    Species reactivity (tested):Human.

    纯化方法

    Protein A Chromatography

    免疫原

    Partial Recombinant RUNX2 (NP_004339, 251 a.a. ~ 351 a.a) protein with GST tag.

    亚型

    IgG2a
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    PBS, pH 7.2

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store the antibody (in aliquots) at -20 °C.
  • 抗原

    RUNX2 (Runt-Related Transcription Factor 2 (RUNX2))

    别名

    RUNX2

    背景

    RUNX family members are DNA-binding proteins that regulate the expression of genes involved in cellular differentiation and cell cycle progression. RUNX2 is essential for skeletal mineralization in that it stimulates osteoblast differentiation of mesenchymal stem cells, promotes chondrocyte hypertrophy and contributes to endothelial cell migration and vascular invasion of developing bones. Regulating RUNX2 expression may be a useful therapeutic tool for promoting bone formation. Mutations in the C-terminus of RUNX2 are associated with cleidocranial dysplasia syndrome, an autosomal-dominant skeletal dysplasia syndrome that is characterized by widely patent calvarial sutures, clavicular hypoplasia, supernumerary teeth, and short stature.Synonyms: AML-3, AML3, Acute myeloid leukemia 3 protein, CBFA1, Core-binding factor subunit alpha-1, OSF-2, OSF2, Osteoblast-specific transcription factor 2, PEA2-alpha A, PEBP2-alpha A, PEBP2A, Polyomavirus enhancer-binding protein 2 alpha A subunit, Runt-related transcription factor 2, SL3-3 enhancer factor 1 alpha A subunit, SL3/AKV core-binding factor alpha A subunit

    基因ID

    860

    NCBI登录号

    NP_001015051

    UniProt

    Q13950
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