PIAS2 抗体 (AA 483-572)
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- 抗原 See all PIAS2 抗体
- PIAS2 (Protein Inhibitor of Activated STAT, 2 (PIAS2))
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抗原表位
- AA 483-572
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PIAS2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- DPPAKRKCIF MSETQSSPTK GVLMYQPSSV RVPSVTSVDP AAIPPSLTDY SVPFHHTPIS SMSSDLPGEQ RRNDINNELK LGTSSDTVQQ
- 交叉反应
- 人, 小鼠
- 产品特性
- Polyclonal Antibodies
- 免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 483-572 of human PIAS2 (NP_775298.1).
- 亚型
- IgG
- Top Product
- Discover our top product PIAS2 Primary Antibody
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- 应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
- 说明
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HIGH QUALITY
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- PIAS2 (Protein Inhibitor of Activated STAT, 2 (PIAS2))
- 别名
- PIAS2 (PIAS2 产品)
- 背景
- This gene encodes a member of the protein inhibitor of activated STAT (PIAS) family. PIAS proteins function as SUMO E3 ligases and play important roles in many cellular processes by mediating the sumoylation of target proteins. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Isoforms of the encoded protein enhance the sumoylation of specific target proteins including the p53 tumor suppressor protein, c-Jun, and the androgen receptor. A pseudogene of this gene is located on the short arm of chromosome 4. The symbol MIZ1 has also been associated with ZBTB17 which is a different gene located on chromosome 1.,PIAS2,ARIP3,DIP,MIZ,MIZ1,PIASX,PIASX-ALPHA,PIASX-BETA,SIZ2,ZMIZ4,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Ubiquitin,Ubiquitin-Proteasome Signaling Pathway,Immunology & Inflammation,IL-6 Receptor Signaling Pathway,PIAS2
- 分子量
- 45 kDa/63 kDa/68 kDa
- 基因ID
- 9063
- UniProt
- O75928
- 途径
- JAK/STAT Signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
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