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PHF19 抗体 (AA 1-207)

PHF19 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6145539
发货至: 中国
  • 抗原 See all PHF19 抗体
    PHF19 (PHD Finger Protein 19 (PHF19))
    抗原表位
    • 9
    • 8
    • 6
    • 2
    • 1
    AA 1-207
    适用
    • 25
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 23
    • 2
    克隆类型
    • 24
    多克隆
    标记
    • 15
    • 2
    • 2
    • 2
    • 2
    • 2
    This PHF19 antibody is un-conjugated
    应用范围
    • 25
    • 17
    • 4
    • 3
    • 2
    • 2
    Western Blotting (WB), Immunofluorescence (IF)
    序列
    MENRALDPGT RDSYGATSHL PNKGALAKVK NNFKDLMSKL TEGQYVLCRW TDGLYYLGKI KRVSSSKQSC LVTFEDNSKY WVLWKDIQHA GVPGEEPKCN ICLGKTSGPL NEILICGKCG LGYHQQCHIP IAGSADQPLL TPWFCRRCIF ALAVRVSLPS SPVPASPASS SGADQRLPSQ SLSSKQKGHT WALETDSASA TVLGQDL
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-207 of human PHF19 (NP_001009936.1).
    亚型
    IgG
    Top Product
    Discover our top product PHF19 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IF,1:50 - 1:100
    说明

    HIGH QUALITY

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    PHF19 (PHD Finger Protein 19 (PHF19))
    别名
    PHF19 (PHF19 产品)
    别名
    si:dkeyp-51b7.1 antibody, pcl3 antibody, MGC147603 antibody, MTF2L1 antibody, PCL3 antibody, TDRD19B antibody, 3110009G19Rik antibody, 3321402G02Rik antibody, PHD finger protein 19 antibody, Phf19 antibody, PHF19 antibody, phf19 antibody
    背景
    Polycomb group (PcG protein that specifically binds histone H3 trimethylated at 'Lys-36' (H3K36me3 and recruits the PRC2 complex, thus enhancing PRC2 H3K27me3 methylation activity. Probably involved in the transition from an active state to a repressed state in embryonic stem cells: acts by binding to H3K36me3, a mark for transcriptional activation, and recruiting H3K36me3 histone demethylases RIOX1 or KDM2B, leading to demethylation of H3K36 and recruitment of the PRC2 complex that mediates H3K27me3 methylation, followed by de novo silencing. Recruits the PRC2 complex to CpG islands and contributes to embryonic stem cell self-renewal. Also binds histone H3 dimethylated at 'Lys-36' (H3K36me2. Isoform 1 and isoform 2 inhibit transcription from an HSV-tk promoter.,PHF19,MTF2L1,PCL3,TDRD19B,Epigenetics & Nuclear Signaling,Transcription Factors,PHF19
    分子量
    14 kDa/22 kDa/65 kDa
    基因ID
    26147
    UniProt
    Q5T6S3
    途径
    Stem Cell Maintenance
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