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PFKFB3 抗体 (AA 400-500)

PFKFB3 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6145485
发货至: 中国
  • 抗原 See all PFKFB3 抗体
    PFKFB3 (6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 3 (PFKFB3))
    抗原表位
    • 15
    • 15
    • 15
    • 11
    • 9
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 400-500
    适用
    • 79
    • 70
    • 65
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    宿主
    • 89
    • 5
    克隆类型
    • 86
    • 10
    多克隆
    标记
    • 36
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    This PFKFB3 antibody is un-conjugated
    应用范围
    • 64
    • 40
    • 40
    • 26
    • 15
    • 15
    • 9
    • 9
    • 6
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    LDKSAEEMPY LKCPLHTVLK LTPVAYGCRV ESIYLNVESV CTHRERSEDA KKGPNPLMRR NSVTPLASPE PTKKPRINSF EEHVASTSAA LPSCLPPEVP T
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    免疫原
    A synthetic peptide corresponding to a sequence within amino acids 400-500 of human PFKFB3 (NP_004557.1).
    亚型
    IgG
    Top Product
    Discover our top product PFKFB3 Primary Antibody
  • 应用备注
    WB,1:500 - 1:1000,IHC,1:50 - 1:100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    PFKFB3 (6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 3 (PFKFB3))
    别名
    PFKFB3 (PFKFB3 产品)
    别名
    IPFK2 antibody, PFK2 antibody, E330010H22Rik antibody, iPFK-2 antibody, uPFK-2 antibody, PFKFB3 antibody, zgc:73257 antibody, wu:fc31e01 antibody, 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 antibody, 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 S homeolog antibody, PFKFB3 antibody, Pfkfb3 antibody, pfkfb3.S antibody, pfkfb3 antibody, PTRG_09894 antibody, Tsp_06710 antibody
    背景
    The protein encoded by this gene belongs to a family of bifunctional proteins that are involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate (F2,6BP), and a fructose-2,6-biphosphatase activity that catalyzes the degradation of F2,6BP. This protein is required for cell cycle progression and prevention of apoptosis. It functions as a regulator of cyclin-dependent kinase 1, linking glucose metabolism to cell proliferation and survival in tumor cells. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.,PFKFB3,IPFK2,PFK2,iPFK-2,Endocrine & Metabolism,Carbohydrate metabolism,AMPK Signaling Pathway,Warburg Effect,PFKFB3
    分子量
    57 kDa/58 kDa/59 kDa/60 kDa
    基因ID
    5209
    UniProt
    Q16875
    途径
    AMPK Signaling, Regulation of Carbohydrate Metabolic Process
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