LIM antibody, Actn2lp antibody, Alp antibody, AI463105 antibody, ALP antibody, alp antibody, hm:zeh1190 antibody, pdlim3 antibody, sb:eu571 antibody, zgc:110415 antibody, PDZ and LIM domain 3 antibody, PDZ and LIM domain 3 S homeolog antibody, PDZ and LIM domain 3b antibody, PDZ and LIM domain 3a antibody, PDLIM3 antibody, Pdlim3 antibody, pdlim3.S antibody, pdlim3b antibody, pdlim3a antibody
背景
The protein encoded by this gene contains a PDZ domain and a LIM domain, indicating that it may be involved in cytoskeletal assembly. In support of this, the encoded protein has been shown to bind the spectrin-like repeats of alpha-actinin-2 and to colocalize with alpha-actinin-2 at the Z lines of skeletal muscle. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Aberrant alternative splicing of this gene may play a role in myotonic dystrophy.,PDLIM3,ALP,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Microfilaments,PDLIM3