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NRARP 抗体 (AA 1-114)

This anti-NRARP antibody is a 兔 多克隆 antibody detecting NRARP in WB. Suitable for 人.
产品编号 ABIN6144838
发货至: 中国

Quick Overview for NRARP 抗体 (AA 1-114) (ABIN6144838)

抗原

See all NRARP 抗体
NRARP (NOTCH-Regulated Ankyrin Repeat Protein (NRARP))

适用

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宿主

  • 33
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克隆类型

  • 35
多克隆

标记

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This NRARP antibody is un-conjugated

应用范围

  • 29
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Western Blotting (WB)
  • 抗原表位

    • 15
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    AA 1-114

    序列

    MSQAELSTCS APQTQRIFQE AVRKGNTQEL QSLLQNMTNC EFNVNSFGPE GQTALHQSVI DGNLELVKLL VKFGADIRLA NRDGWSALHI AAFGGHQDIV LYLITKAKYA ASGR

    交叉反应

    小鼠

    产品特性

    Polyclonal Antibodies

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 1-114 of human NRARP (NP_001004354.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    NRARP (NOTCH-Regulated Ankyrin Repeat Protein (NRARP))

    别名

    NRARP

    背景

    Downstream effector of Notch signaling. Involved in the regulation of liver cancer cells self-renewal. Involved in angiogenesis acting downstream of Notch at branch points to regulate vascular density. Proposed to integrate endothelial Notch and Wnt signaling to control stalk cell proliferation and to stablilize new endothelial connections during angiogenesis. During somitogenesis involved in maintenance of proper somite segmentation and proper numbers of somites and vertebrae. Required for proper anterior-posterior somite patterning. Proposed to function in a negative feedback loop to destabilize Notch 1 intracellular domain (NICD and downregulate the Notch signal, preventing expansion of the Notch signal into the anterior somite domain (By similarity.,NRARP,Cell Biology & Developmental Biology,Neuroscience,Cardiovascular,Angiogenesis,NRARP

    分子量

    12 kDa

    基因ID

    441478

    UniProt

    Q7Z6K4
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