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NAA50 抗体 (AA 1-169)

NAA50 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6144327
发货至: 中国
  • 抗原 See all NAA50 抗体
    NAA50 (N(alpha)-Acetyltransferase 50, NatE Catalytic Subunit (NAA50))
    抗原表位
    • 9
    • 8
    • 6
    • 2
    • 2
    AA 1-169
    适用
    • 23
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 23
    克隆类型
    • 23
    多克隆
    标记
    • 13
    • 2
    • 2
    • 2
    • 2
    • 2
    This NAA50 antibody is un-conjugated
    应用范围
    • 21
    • 14
    • 13
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    序列
    MKGSRIELGD VTPHNIKQLK RLNQVIFPVS YNDKFYKDVL EVGELAKLAY FNDIAVGAVC CRVDHSQNQK RLYIMTLGCL APYRRLGIGT KMLNHVLNIC EKDGTFDNIY LHVQISNESA IDFYRKFGFE IIETKKNYYK RIEPADAHVL QKNLKVPSGQ NADVQKTDN
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-169 of human NAA50 (NP_079422.1).
    亚型
    IgG
    Top Product
    Discover our top product NAA50 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IF,1:50 - 1:200
    说明

    HIGH QUALITY

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    NAA50 (N(alpha)-Acetyltransferase 50, NatE Catalytic Subunit (NAA50))
    别名
    NAA50 (NAA50 产品)
    别名
    MAK3 antibody, NAT13 antibody, NAT5 antibody, SAN antibody, hNAT5 antibody, hSAN antibody, 2600005K24Rik antibody, 2810441M03Rik antibody, AW112078 antibody, Mak3 antibody, Mak3p antibody, Nat13 antibody, Nat5 antibody, San antibody, DKFZp469M1032 antibody, san antibody, mak3 antibody, nat5 antibody, nat13 antibody, MGC80671 antibody, N(alpha)-acetyltransferase 50, NatE catalytic subunit antibody, N(alpha)-acetyltransferase 50, NatE catalytic subunit L homeolog antibody, NAA50 antibody, Naa50 antibody, naa50.L antibody
    背景
    N-alpha-acetyltransferase that acetylates the N-terminus of proteins that retain their initiating methionine. Has a broad substrate specificity: able to acetylate the initiator methionine of most peptides, except for those with a proline in second position. Also displays N-epsilon-acetyltransferase activity by mediating acetylation of the side chain of specific lysines on proteins. Autoacetylates in vivo. The relevance of N-epsilon-acetyltransferase activity is however unclear: able to acetylate H4 in vitro, but this result has not been confirmed in vivo. Component of N-alpha-acetyltransferase complexes containing NAA10 and NAA15, which has N-alpha-acetyltransferase activity. Does not influence the acetyltransferase activity of NAA10. However, it negatively regulates the N-alpha-acetyltransferase activity of the N-terminal acetyltransferase A complex (also called the NatA complex. The multiprotein complexes probably constitute the major contributor for N-terminal acetylation at the ribosome exit tunnel, with NAA10 acetylating all amino termini that are devoid of methionine and NAA50 acetylating other peptides. Required for sister chromatid cohesion during mitosis by promoting binding of CDCA5/sororin to cohesin: may act by counteracting the function of NAA10.,NAA50,MAK3,NAT13,NAT13P,NAT5,NAT5P,SAN,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,NAA50
    分子量
    9 kDa/19 kDa
    基因ID
    80218
    UniProt
    Q9GZZ1
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