MRPS12 抗体 (AA 30-138)
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- 抗原 See all MRPS12 抗体
- MRPS12 (Mitochondrial Ribosomal Protein S12 (MRPS12))
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抗原表位
- AA 30-138
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MRPS12 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- MATLNQMHRL GPPKRPPRKL GPTEGRPQLK GVVLCTFTRK PKKPNSANRK CCRVRLSTGR EAVCFIPGEG HTLQEHQIVL VEGGRTQDLP GVKLTVVRGK YDCGHVQKK
- 交叉反应
- 人
- 产品特性
- Polyclonal Antibodies
- 免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 30-138 of human MRPS12 (NP_203527.1).
- 亚型
- IgG
- Top Product
- Discover our top product MRPS12 Primary Antibody
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- 应用备注
- WB,1:1000 - 1:2000,IHC,1:50 - 1:200
- 说明
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HIGH QUALITY
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- MRPS12 (Mitochondrial Ribosomal Protein S12 (MRPS12))
- 别名
- MRPS12 (MRPS12 产品)
- 背景
- Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S12P family. The encoded protein is a key component of the ribosomal small subunit and controls the decoding fidelity and susceptibility to aminoglycoside antibiotics. The gene for mitochondrial seryl-tRNA synthetase is located upstream and adjacent to this gene, and both genes are possible candidates for the autosomal dominant deafness gene (DFNA4). Splice variants that differ in the 5' UTR have been found for this gene, all three variants encode the same protein.,MRPS12,MPR-S12,MT-RPS12,RPMS12,RPS12,RPSM12,Epigenetics & Nuclear Signaling,MRPS12
- 分子量
- 15 kDa
- 基因ID
- 6183
- UniProt
- O15235
- 途径
- Sensory Perception of Sound
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