MID1 抗体 (AA 478-667)
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- 抗原 See all MID1 抗体
- MID1 (Midline 1 (MID1))
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抗原表位
- AA 478-667
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MID1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF)
- 序列
- KLKTNSQPFK LDPKSAHRKL KVSHDNLTVE RDESSSKKSH TPERFTSQGS YGVAGNVFID SGRHYWEVVI SGSTWYAIGL AYKSAPKHEW IGKNSASWAL CRCNNNWVVR HNSKEIPIEP APHLRRVGIL LDYDNGSIAF YDALNSIHLY TFDVAFAQPV CPTFTVWNKC LTIITGLPIP DHLDCTEQLP
- 交叉反应
- 人, 小鼠
- 产品特性
- Polyclonal Antibodies
- 免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 478-667 of human MID1 (NP_000372.1).
- 亚型
- IgG
- Top Product
- Discover our top product MID1 Primary Antibody
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- 应用备注
- WB,1:500 - 1:2000,IF,1:50 - 1:100
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- MID1 (Midline 1 (MID1))
- 别名
- MID1 (MID1 产品)
- 背景
- The protein encoded by this gene is a member of the tripartite motif (TRIM) family, also known as the 'RING-B box-coiled coil' (RBCC) subgroup of RING finger proteins. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein forms homodimers which associate with microtubules in the cytoplasm. The protein is likely involved in the formation of multiprotein structures acting as anchor points to microtubules. Mutations in this gene have been associated with the X-linked form of Opitz syndrome, which is characterized by midline abnormalities such as cleft lip, laryngeal cleft, heart defects, hypospadias, and agenesis of the corpus callosum. This gene was also the first example of a gene subject to X inactivation in human while escaping it in mouse. Alternative promoter use, alternative splicing and alternative polyadenylation result in multiple transcript variants that have different tissue specificities.,MID1,BBBG1,FXY,GBBB1,MIDIN,OGS1,OS,OSX,RNF59,TRIM18,XPRF,ZNFXY,midline 1,Cell Biology & Developmental Biology,Ubiquitin,Ubiquitin-Proteasome Signaling Pathway,MID1
- 分子量
- 62 kDa/75 kDa
- 基因ID
- 4281
- UniProt
- O15344
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