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MCM4 抗体 (AA 350-450)

MCM4 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6143642
发货至: 中国
  • 抗原 See all MCM4 抗体
    MCM4 (Minichromosome Maintenance Deficient 4 (MCM4))
    抗原表位
    • 15
    • 11
    • 8
    • 7
    • 6
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 350-450
    适用
    • 92
    • 43
    • 22
    • 10
    • 10
    • 10
    • 9
    • 8
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    宿主
    • 86
    • 4
    • 3
    克隆类型
    • 91
    • 2
    多克隆
    标记
    • 51
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MCM4 antibody is un-conjugated
    应用范围
    • 71
    • 36
    • 35
    • 13
    • 13
    • 13
    • 9
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    QMIKLQESPE DMPAGQTPHT VILFAHNDLV DKVQPGDRVN VTGIYRAVPI RVNPRVSNVK SVYKTHIDVI HYRKTDAKRL HGLDEEAEQK LFSEKRVELL K
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    免疫原
    A synthetic peptide corresponding to a sequence within amino acids 350-450 of human MCM4 (NP_877423.1).
    亚型
    IgG
    Top Product
    Discover our top product MCM4 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IHC,1:100 - 1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    MCM4 (Minichromosome Maintenance Deficient 4 (MCM4))
    别名
    MCM4 (MCM4 产品)
    别名
    cdc21 antibody, CDC21 antibody, CDC54 antibody, NKCD antibody, NKGCD antibody, P1-CDC21 antibody, hCdc21 antibody, 19G antibody, AI325074 antibody, AU045576 antibody, Cdc21 antibody, Mcmd4 antibody, mKIAA4003 antibody, mcdc21 antibody, cb1025 antibody, fc12c09 antibody, fj85g09 antibody, hm:zeh1616 antibody, wu:fc12c09 antibody, wu:fj85g09 antibody, zeh1616 antibody, minichromosome maintenance complex component 4 L homeolog antibody, minichromosome maintenance complex component 4 S homeolog antibody, minichromosome maintenance complex component 4 antibody, mcm4.L antibody, mcm4.S antibody, MCM4 antibody, mcm4 antibody, Mcm4 antibody
    背景
    The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 6 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of this protein by CDC2 kinase reduces the DNA helicase activity and chromatin binding of the MCM complex. This gene is mapped to a region on the chromosome 8 head-to-head next to the PRKDC/DNA-PK, a DNA-activated protein kinase involved in the repair of DNA double-strand breaks. Alternatively spliced transcript variants encoding the same protein have been reported.,MCM4,CDC21,CDC54,NKCD,NKGCD,P1-CDC21,hCdc21,Epigenetics & Nuclear Signaling,MCM4
    分子量
    96 kDa
    基因ID
    4173
    UniProt
    P33991
    途径
    DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA
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