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ERK2 抗体 (AA 200-300)

MAPK1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6143516
发货至: 中国
  • 抗原 See all ERK2 (MAPK1) 抗体
    ERK2 (MAPK1) (Mitogen-Activated Protein Kinase 1 (MAPK1))
    抗原表位
    • 12
    • 8
    • 8
    • 7
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 200-300
    适用
    • 113
    • 56
    • 54
    • 13
    • 8
    • 6
    • 6
    • 6
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    宿主
    • 82
    • 30
    • 4
    • 3
    • 1
    克隆类型
    • 78
    • 43
    多克隆
    标记
    • 81
    • 9
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    This ERK2 antibody is un-conjugated
    应用范围
    • 88
    • 55
    • 42
    • 26
    • 23
    • 21
    • 9
    • 8
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    序列
    LNSKGYTKSI DIWSVGCILA EMLSNRPIFP GKHYLDQLNH ILGILGSPSQ EDLNCIINLK ARNYLLSLPH KNKVPWNRLF PNADSKALDL LDKMLTFNPH K
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    免疫原
    A synthetic peptide corresponding to a sequence within amino acids 200-300 of human ERK2 (NP_620407.1).
    亚型
    IgG
    Top Product
    Discover our top product MAPK1 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
    说明

    HIGH QUALITY

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • Wang, Zhang, Sun, Tong, Ren: "Rutin Protects against Pirarubicin-Induced Cardiotoxicity through TGF-β1-p38 MAPK Signaling Pathway." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2017, pp. 1759385, (2017) (PubMed).

  • 抗原
    ERK2 (MAPK1) (Mitogen-Activated Protein Kinase 1 (MAPK1))
    别名
    MAPK1 (MAPK1 产品)
    背景
    This gene encodes a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. One study also suggests that this protein acts as a transcriptional repressor independent of its kinase activity. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene.,ERK,ERK-2,ERK2,ERT1,MAPK2,P42MAPK,PRKM1,PRKM2,p38,p40,p41,p41mapk,p42-MAPK,MAPK1,Epigenetics & Nuclear Signaling,Translation Control,Regulation of eIF4 and p70 S6 Kinase,Signal Transduction,G protein signaling,G2/M DNA Damage Checkpoint,Kinase,Serine/threonine kinases,mTOR Signaling Pathway,ErbB-HER Signaling Pathway,MAPK-Erk Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Mitochondrial Control of Apoptosis,Inhibition of Apoptosis,Cell Cycle,Centromere,Microtubules,TGF-b-Smad Signaling Pathway,ESC Pluripotency and Differentiation,Endocrine & Metabolism,Insulin Receptor Signaling Pathway,Warburg Effect,Immunology & Inflammation,B Cell Receptor Signaling Pathway,T Cell Receptor Signaling Pathway,IL-6 Receptor Signaling Pathway,Neuroscience,Neurodegenerative Diseases,Stem Cells,Cardiovascular,Angiogenesis,MAPK1
    分子量
    36 kDa/41 kDa
    基因ID
    5594
    UniProt
    P28482
    途径
    MAPK Pathway, RTK signaling, Apoptosis, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, Response to Growth Hormone Stimulus, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Monocarboxylic Acid Catabolic Process, Autophagy, G-protein mediated Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals, BCR Signaling, S100 Proteins
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