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LAMB2 抗体 (AA 1579-1798)

LAMB2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6143070
发货至: 中国
  • 抗原 See all LAMB2 抗体
    LAMB2 (Laminin, beta 2 (Laminin S) (LAMB2))
    抗原表位
    • 15
    • 8
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1579-1798
    适用
    • 49
    • 18
    • 16
    宿主
    • 55
    • 2
    克隆类型
    • 55
    • 2
    多克隆
    标记
    • 23
    • 7
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This LAMB2 antibody is un-conjugated
    应用范围
    • 31
    • 22
    • 21
    • 13
    • 13
    • 7
    • 7
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    序列
    DVRRAEQLLQ DARRARSWAE DEKQKAETVQ AALEEAQRAQ GIAQGAIRGA VADTRDTEQT LYQVQERMAG AERALSSAGE RARQLDALLE ALKLKRAGNS LAASTAEETA GSAQGRAQEA EQLLRGPLGD QYQTVKALAE RKAQGVLAAQ ARAEQLRDEA RDLLQAAQDK LQRLQELEGT YEENERALES KAAQLDGLEA RMRSVLQAIN LQVQIYNTCQ
    交叉反应
    人, 小鼠
    产品特性
    Polyclonal Antibodies
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 1579-1798 of human LAMB2 (NP_002283.3).
    亚型
    IgG
    Top Product
    Discover our top product LAMB2 Primary Antibody
  • 应用备注
    WB,1:1000 - 1:2000,IF,1:50 - 1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    LAMB2 (Laminin, beta 2 (Laminin S) (LAMB2))
    别名
    LAMB2 (LAMB2 产品)
    别名
    LAMS antibody, NPHS5 antibody, AW211941 antibody, Lamb-2 antibody, Lams antibody, SLAM antibody, lamb1 antibody, lams antibody, LAMC1 antibody, laminin antibody, laminin subunit beta 2 antibody, laminin, beta 2 antibody, laminin subunit beta 2 L homeolog antibody, laminin, beta 2 (laminin S) antibody, LAMB2 antibody, Lamb2 antibody, lamb2.L antibody
    背景
    Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins, composed of 3 non identical chains: laminin alpha, beta and gamma . Some of the chains have been shown to differ with respect to their tissue distribution, presumably reflecting diverse functions in vivo. This gene encodes the beta chain isoform laminin, beta 2. The beta 2 chain contains the 7 structural domains typical of beta chains of laminin, including the short alpha region. However, unlike beta 1 chain, beta 2 has a more restricted tissue distribution. It is enriched in the basement membrane of muscles at the neuromuscular junctions, kidney glomerulus and vascular smooth muscle. Transgenic mice in which the beta 2 chain gene was inactivated by homologous recombination, showed defects in the maturation of neuromuscular junctions and impairment of glomerular filtration. Alternative splicing involving a non consensus 5' splice site (gc) in the 5' UTR of this gene has been reported. It was suggested that inefficient splicing of this first intron, which does not change the protein sequence, results in a greater abundance of the unspliced form of the transcript than the spliced form.,LAMB2,LAMS,NPHS5,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Cytoskeleton,Intermediate Filaments,Extracellular Matrix,Neuroscience,Cardiovascular,Angiogenesis,LAMB2
    分子量
    195 kDa
    基因ID
    3913
    UniProt
    P55268
    途径
    Skeletal Muscle Fiber Development
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