KPNB1 抗体 (AA 250-350)
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- 抗原 See all KPNB1 抗体
- KPNB1 (Karyopherin (Importin) beta 1 (KPNB1))
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抗原表位
- AA 250-350
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This KPNB1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- 序列
- QYMETYMGPA LFAITIEAMK SDIDEVALQG IEFWSNVCDE EMDLAIEASE AAEQGRPPEH TSKFYAKGAL QYLVPILTQT LTKQDENDDD DDWNPCKAAG V
- 交叉反应
- 人, 小鼠, 大鼠
- 产品特性
- Polyclonal Antibodies
- 免疫原
- A synthetic peptide corresponding to a sequence within amino acids 250-350 of human KPNB1 (NP_002256.2).
- 亚型
- IgG
- Top Product
- Discover our top product KPNB1 Primary Antibody
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- 应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:200
- 说明
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HIGH QUALITY
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- KPNB1 (Karyopherin (Importin) beta 1 (KPNB1))
- 别名
- KPNB1 (KPNB1 产品)
- 背景
- Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. Interactions between importin beta and the FG repeats of nucleoporins are essential in translocation through the pore complex. The protein encoded by this gene is a member of the importin beta family. Two transcript variants encoding different isoforms have been found for this gene.,KPNB1,IMB1,IPO1,IPOB,Impnb,NTF97,Epigenetics & Nuclear Signaling,Nuclear Receptor Signaling,Signal Transduction,ErbB-HER Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Endocrine & Metabolism,Lipid Metabolism,Immunology & Inflammation,KPNB1
- 分子量
- 81 kDa/97 kDa
- 基因ID
- 3837
- UniProt
- Q14974
- 途径
- Protein targeting to Nucleus
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