This gene encodes a hematopoietic-specific transcription factor that induces high-level expression of adult beta-globin and other erythroid genes. The zinc-finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss-of-function mutations in this gene result in the dominant In(Lu) blood phenotype.,KLF1,EKLF,CDAN4,HBFQTL6,INLU,Epigenetics & Nuclear Signaling,Transcription Factors,KLF1