nlg1 antibody, neph3 antibody, filtrin antibody, FILTRIN antibody, NEPH3 antibody, NLG1 antibody, C330019F22Rik antibody, cb33 antibody, kirrel3 antibody, sb:cb33 antibody, si:dkey-29g23.1 antibody, wu:fb74e02 antibody, kirre like nephrin family adhesion molecule 2 antibody, kin of IRRE like 2 (Drosophila) antibody, kirre like nephrin family adhesion molecule 3, like antibody, kirrel2 antibody, KIRREL2 antibody, Kirrel2 antibody, kirrel3l antibody
背景
This gene encodes a type I transmembrane protein and member of the immunoglobulin superfamily of cell adhesion molecules. The encoded protein localizes to adherens junctions in pancreatic beta cells and regulates insulin secretion. Autoantibodies against the encoded protein have been detected in serum from patients with type 1 diabetes. This gene may also play a role in glomerular development and decreased expression of this gene has been observed in human glomerular diseases. This gene and the related opposite-strand gene nephrin (GeneID: 527362) are regulated by a bidirectional promoter.,KIRREL2,FILTRIN,NEPH3,NLG1,Cell Biology & Developmental Biology,KIRREL2