KHDRBS3 抗体 (AA 177-346)
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- 抗原 See all KHDRBS3 抗体
- KHDRBS3 (KH Domain Containing, RNA Binding, Signal Transduction Associated 3 (KHDRBS3))
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抗原表位
- AA 177-346
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This KHDRBS3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF)
- 序列
- GSENADVPVV RGKPTLRTRG VPAPAITRGR GGVTARPVGV VVPRGTPTPR GVLSTRGPVS RGRGLLTPRA RGVPPTGYRP PPPPPTQETY GEYDYDDGYG TAYDEQSYDS YDNSYSTPAQ SGADYYDYGH GLSEETYDSY GQEEWTNSRH KAPSARTAKG VYRDQPYGRY
- 交叉反应
- 人, 小鼠
- 产品特性
- Polyclonal Antibodies
- 免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 177-346 of human KHDRBS3 (NP_006549.1).
- 亚型
- IgG
- Top Product
- Discover our top product KHDRBS3 Primary Antibody
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- 应用备注
- WB,1:500 - 1:2000,IF,1:50 - 1:100
- 说明
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HIGH QUALITY
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- KHDRBS3 (KH Domain Containing, RNA Binding, Signal Transduction Associated 3 (KHDRBS3))
- 别名
- KHDRBS3 (KHDRBS3 产品)
- 别名
- KHDRBS3 antibody, T-STAR antibody, Etle antibody, SALP antibody, SLM-2 antibody, SLM2 antibody, TSTAR antibody, etoile antibody, Slm2 antibody, KH domain containing, RNA binding, signal transduction associated 3 antibody, KH RNA binding domain containing, signal transduction associated 3 antibody, KHDRBS3 antibody, Khdrbs3 antibody
- 背景
- RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. Binds preferentially to the 5'-[AU]UAAA-3' motif in vitro. Binds optimally to RNA containing 5'-[AU]UAA-3' as a bipartite motif spaced by more than 15 nucleotides. Binds poly(A. RNA-binding abilities are down-regulated by tyrosine kinase PTK6. Involved in splice site selection of vascular endothelial growth factor. In vitro regulates CD44 alternative splicing by direct binding to purine-rich exonic enhancer (By similarity. Can regulate alternative splicing of neurexins NRXN1-3 in the laminin G-like domain 6 containing the evolutionary conserved neurexin alternative spliced segment 4 (AS4 involved in neurexin selective targeting to postsynaptic partners such as neuroligins and LRRTM family members. Targeted, cell-type specific splicing regulation of NRXN1 at AS4 is involved in neuronal glutamatergic synapse function and plasticity (By similarity. May regulate expression of KHDRBS2/SLIM-1 in defined brain neuron populations by modifying its alternative splicing (By similarity. Can bind FABP9 mRNA (By similarity. May play a role as a negative regulator of cell growth. Inhibits cell proliferation.,KHDRBS3,Etle,SALP,SLM-2,SLM2,T-STAR,TSTAR,etoile,Epigenetics & Nuclear Signaling,KHDRBS3
- 分子量
- 30 kDa/38 kDa
- 基因ID
- 10656
- UniProt
- O75525
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