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VEGFR2/CD309 抗体 (AA 20-200)

Name: VEGFR2/CD309 抗体 (AA 20-200)
Brand: antibodies-online
SKU: ABIN6142816
Availability: OutOfStock

VEGFR2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

Western blot analysis of extracts of various cell lines, using VEGF Receptor 2 antibody (ABIN6132247, ABIN6142816, ABIN6142819 and ABIN6215074) at 1:500 dilution. (VEGFR2/CD309 抗体 (AA 20-200))

Immunohistochemistry of paraffin-embedded mouse testis using VEGF Receptor 2 antibody (ABIN6132247, ABIN6142816, ABIN6142819 and ABIN6215074) at dilution of 1:100 (40x lens). (VEGFR2/CD309 抗体 (AA 20-200))

IHC

Western blot analysis of extracts of A-549 cells, using VEGF Receptor 2 antibody (ABIN6132247, ABIN6142816, ABIN6142819 and ABIN6215074) at 1:500 dilution. (VEGFR2/CD309 抗体 (AA 20-200))

Immunohistochemistry of paraffin-embedded rat testis using VEGF Receptor 2 antibody (ABIN6132247, ABIN6142816, ABIN6142819 and ABIN6215074) at dilution of 1:100 (40x lens). (VEGFR2/CD309 抗体 (AA 20-200))

IHC

Immunohistochemistry of paraffin-embedded mouse brain using VEGF Receptor 2 antibody (ABIN6132247, ABIN6142816, ABIN6142819 and ABIN6215074) at dilution of 1:100 (40x lens). (VEGFR2/CD309 抗体 (AA 20-200))

IHC

5 images

(1 reference)

产品编号 ABIN6142816

发货至: 中国

Datasheet as PDF

Key Features
- High quality VEGFR2/CD309 Primary Antibody for the detection of VEGFR2.
- Reliable product with high standard validation data
抗原 See all VEGFR2/CD309 (VEGFR2) 抗体

VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))
抗原表位
42

36

27

25

20

16

16

15

15

10

10

8

8

6

6

6

5

5

4

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 20-200
适用
312

199

145

17

9

5

3

3

3

3

1

1

1

1

1

1

1

1

1

1
人
宿主
304

51

15

1

1

1
兔
Compatible Secondaries
克隆类型
297

76
多克隆
标记
162

34

20

13

13

12

7

7

7

7

7

7

6

6

6

6

6

6

6

6

6

6

6

2

2

1

1

1

1

1

1

1
This VEGFR2/CD309 antibody is un-conjugated
应用范围
223

135

96

85

64

27

26

22

19

14

13

12

9

8

7

4

3

2

1
Western Blotting (WB), Immunohistochemistry (IHC)

序列

ASVGLPSVSL DLPRLSIQKD ILTIKANTTL QITCRGQRDL DWLWPNNQSG SEQRVEVTEC SDGLFCKTLT IPKVIGNDTG AYKCFYRETD LASVIYVYVQ DYRSPFIASV SDQHGVVYIT ENKNKTVVIP CLGSISNLNV SLCARYPEKR FVPDGNRISW DSKKGFTIPS YMISYAGMVF C

交叉反应

人, 小鼠, 大鼠

产品特性

Polyclonal Antibodies

免疫原

Recombinant fusion protein containing a sequence corresponding to amino acids 20-200 of human VEGF Receptor 2 (NP_002244.1).

亚型

IgG

Product Specific Information

What can the VEGFR2/CD309 Antibody ABIN6142816 be used for?

This polyclonal VEGFR2/CD309 Antibody detects VEGFR2/CD309. The VEGFR2/CD309 Antibody has been validated for various applications and can be used for the detection of VEGFR2/CD309 and derivatives by Western Blotting, Immunohistochemistry.

What validation data is available for this VEGFR2/CD309 Antibody?

The Primary Antibody is referenced in 1 publications and is characterized by a proven, very high reliability. It has currently 5 product images that show its performance in a variety of applications. The product is currently available in 20 μL, 100 μL quantities. VEGFR2/CD309 Antibody for the detection of VEGFR2/CD309 and derivatives.

What is the function of VEGFR2/CD309?

Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas. [provided by RefSeq, May 2009].
anti-VEGF Receptor 2 (VEGFR2) (pTyr951) antibody
VEGFR2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-VEGF Receptor 2 (VEGFR2) (AA 20-242) antibody
VEGFR2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-VEGF Receptor 2 (VEGFR2) (AA 1326-1356) antibody
VEGFR2 适用: 人 WB, IHC, ELISA, FACS, IF 宿主: 兔 Polyclonal unconjugated

anti-VEGF Receptor 2 (VEGFR2) (AA 101-200) antibody
VEGFR2 适用: 人, 小鼠, 大鼠, 兔 ELISA, FACS, IHC (p), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-VEGF Receptor 2 (VEGFR2) (pTyr1214) antibody
VEGFR2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-VEGF Receptor 2 (VEGFR2) (AA 20-764) antibody
VEGFR2 适用: 人 WB, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 4B4 unconjugated

anti-VEGF Receptor 2 (VEGFR2) (AA 1225-1356) antibody
VEGFR2 适用: 人 WB, IHC, ELISA, FACS, ICC, Neut 宿主: 小鼠 Monoclonal 1A9A3 unconjugated

anti-VEGF Receptor 2 (VEGFR2) (AA 454-469), (Middle Region) antibody
VEGFR2 适用: 人 WB, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-VEGF Receptor 2 (VEGFR2) (AA 1326-1356), (C-Term) antibody
VEGFR2 适用: 人 WB, FACS, IF, IHC (p) 宿主: 兔 Polyclonal RB01536 unconjugated

anti-VEGF Receptor 2 (VEGFR2) (AA 46-320) antibody
VEGFR2 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

WB,1:500 - 1:2000,IHC,1:50 - 1:200

说明

HIGH QUALITY

限制

仅限研究用
状态

Liquid

缓冲液

PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store at -20°C. Avoid freeze / thaw cycles.
Ding, Shan, Nai, Lin, Zhou, Dong, Wu, Xiao, Zhou, Wang, Li, Fu, Lin, Jia, Dai, Bai: "DEPTOR Deficiency-Mediated mTORc1 Hyperactivation in Vascular Endothelial Cells Promotes Angiogenesis." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 46, Issue 2, pp. 520-531, (2018) (PubMed).
抗原

VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))

别名

KDR (VEGFR2 产品)

别名

CD309 antibody, FLK1 antibody, VEGFR antibody, VEGFR2 antibody, 6130401C07 antibody, Flk-1 antibody, Flk1 antibody, Krd-1 antibody, Ly73 antibody, VEGFR-2 antibody, sVEGFR-2 antibody, Vegfr-2 antibody, FLK-1 antibody, flk-1 antibody, vegfr-2 antibody, KDR antibody, FLK/KDR antibody, flk1 antibody, flk1b antibody, kdrb antibody, si:busm1-205d10.1 antibody, si:ch211-254j6.1 antibody, si:ch211-278f21.4 antibody, wu:fc31a09 antibody, fk52c05 antibody, flk antibody, kdr antibody, kdra antibody, vegfr2 antibody, vegfr4 antibody, vegr2 antibody, wu:fk52c05 antibody, kinase insert domain receptor antibody, kinase insert domain protein receptor antibody, vascular endothelial growth factor receptor kdr-like antibody, kinase insert domain receptor (a type III receptor tyrosine kinase) antibody, kinase insert domain receptor like antibody, KDR antibody, Kdr antibody, LOC100136647 antibody, kdr antibody, kdrl antibody

背景

Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas.,CD309,FLK1,VEGFR,VEGFR2,VEGF Receptor 2,KDR,Cancer,Invasion and Metastasis,Signal Transduction,Kinase,Tyrosine kinases,Cell Biology & Developmental Biology,Growth factor,VEGF,VEGF Receptors,Endocrine & Metabolism,Immunology & Inflammation,CD markers,Stem Cells,Endothelial Progenitors,Hematopoietic Progenitors,Cardiovascular,Angiogenesis,Angiogenic growth factors,Hypoxia,KDR

分子量

75 kDa/79 kDa/151 kDa

基因ID

3791

UniProt

P35968

途径

RTK signaling, Glycosaminoglycan Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling