KCNN3 抗体 (AA 237-426)
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- 抗原 See all KCNN3 抗体
- KCNN3 (Small Conductance Calcium-Activated Potassium Channel Protein 3 (KCNN3))
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抗原表位
- AA 237-426
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This KCNN3 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- VARKLELTKA EKHVHNFMMD TQLTKRIKNA AANVLRETWL IYKHTKLLKK IDHAKVRKHQ RKFLQAIHQL RSVKMEQRKL SDQANTLVDL SKMQNVMYDL ITELNDRSED LEKQIGSLES KLEHLTASFN SLPLLIADTL RQQQQQLLSA IIEARGVSVA VGTTHTPISD SPIGVSSTSF PTPYTSSSSC
- 交叉反应
- 人
- 产品特性
- Polyclonal Antibodies
- 免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 237-426 of human KCNN3 (NP_740752.1).
- 亚型
- IgG
- Top Product
- Discover our top product KCNN3 Primary Antibody
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- 应用备注
- WB,1:500 - 1:2000
- 说明
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HIGH QUALITY
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- KCNN3 (Small Conductance Calcium-Activated Potassium Channel Protein 3 (KCNN3))
- 别名
- KCNN3 (KCNN3 产品)
- 别名
- KCa2.3 antibody, SK3 antibody, SKCA3 antibody, hSK3 antibody, potassium calcium-activated channel subfamily N member 3 antibody, potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3 antibody, Kcnn3 antibody, KCNN3 antibody
- 背景
- Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. This gene belongs to the KCNN family of potassium channels. It encodes an integral membrane protein that forms a voltage-independent calcium-activated channel, which is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. This gene contains two CAG repeat regions in the coding sequence. It was thought that expansion of one or both of these repeats could lead to an increased susceptibility to schizophrenia or bipolar disorder, but studies indicate that this is probably not the case. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,KCNN3,KCa2.3,SK3,SKCA3,hSK3,Signal Transduction,Neuroscience,KCNN3
- 分子量
- 47 kDa/48 kDa/82 kDa
- 基因ID
- 3782
- UniProt
- Q9UGI6
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