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IL17RA 抗体 (AA 697-866)

IL17RA 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6142322
发货至: 中国
  • 抗原 See all IL17RA 抗体
    IL17RA (Interleukin 17 Receptor A (IL17RA))
    抗原表位
    • 15
    • 7
    • 7
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 697-866
    适用
    • 55
    • 51
    • 11
    宿主
    • 67
    • 8
    • 4
    • 3
    克隆类型
    • 69
    • 13
    多克隆
    标记
    • 33
    • 8
    • 8
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IL17RA antibody is un-conjugated
    应用范围
    • 63
    • 36
    • 13
    • 13
    • 9
    • 8
    • 7
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    序列
    AGEGEACPLL GSPGAGRNSV LFLPVDPEDS PLGSSTPMAS PDLLPEDVRE HLEGLMLSLF EQSLSCQAQG GCSRPAMVLT DPHTPYEEEQ RQSVQSDQGY ISRSSPQPPE GLTEMEEEEE EEQDPGKPAL PLSPEDLESL RSLQRQLLFR QLQKNSGWDT MGSESEGPSA
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 697-866 of human IL17RA (NP_055154.3).
    亚型
    IgG
    Top Product
    Discover our top product IL17RA Primary Antibody
  • 应用备注
    WB,1:1000 - 1:4000
    说明

    HIGH QUALITY

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • Ganesan, Rasool: "Interleukin 17 regulates SHP-2 and IL-17RA/STAT-3 dependent Cyr61, IL-23 and GM-CSF expression and RANKL mediated osteoclastogenesis by fibroblast-like synoviocytes in rheumatoid arthritis." in: Molecular immunology, Vol. 91, pp. 134-144, (2017) (PubMed).

  • 抗原
    IL17RA (Interleukin 17 Receptor A (IL17RA))
    别名
    IL17RA (IL17RA 产品)
    别名
    IL17R antibody, CANDF5 antibody, CD217 antibody, CDw217 antibody, IL-17RA antibody, hIL-17R antibody, Il17r antibody, AW538159 antibody, Cdw217 antibody, VDw217 antibody, interleukin 17 receptor A antibody, IL17RA antibody, Il17ra antibody
    背景
    Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor, IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Alternative splicing results in multiple transcript variants encoding different isoforms.,IL17RA,CANDF5,CD217,CDw217,IL-17RA,IL17R,IMD51,hIL-17R,Immunology & Inflammation,CD markers,Cytokines,Interleukins,Cell Intrinsic Innate Immunity Signaling Pathway,IL17RA
    分子量
    92 kDa/96 kDa
    基因ID
    23765
    UniProt
    Q96F46
    途径
    SARS-CoV-2 Protein Interactome
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