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- 抗原 See all IL17RA 抗体
- IL17RA (Interleukin 17 Receptor A (IL17RA))
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抗原表位
- AA 697-866
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This IL17RA antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- AGEGEACPLL GSPGAGRNSV LFLPVDPEDS PLGSSTPMAS PDLLPEDVRE HLEGLMLSLF EQSLSCQAQG GCSRPAMVLT DPHTPYEEEQ RQSVQSDQGY ISRSSPQPPE GLTEMEEEEE EEQDPGKPAL PLSPEDLESL RSLQRQLLFR QLQKNSGWDT MGSESEGPSA
- 交叉反应
- 人, 小鼠, 大鼠
- 产品特性
- Polyclonal Antibodies
- 免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 697-866 of human IL17RA (NP_055154.3).
- 亚型
- IgG
- Top Product
- Discover our top product IL17RA Primary Antibody
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- 应用备注
- WB,1:1000 - 1:4000
- 说明
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HIGH QUALITY
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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Interleukin 17 regulates SHP-2 and IL-17RA/STAT-3 dependent Cyr61, IL-23 and GM-CSF expression and RANKL mediated osteoclastogenesis by fibroblast-like synoviocytes in rheumatoid arthritis." in: Molecular immunology, Vol. 91, pp. 134-144, (2017) (PubMed).
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Interleukin 17 regulates SHP-2 and IL-17RA/STAT-3 dependent Cyr61, IL-23 and GM-CSF expression and RANKL mediated osteoclastogenesis by fibroblast-like synoviocytes in rheumatoid arthritis." in: Molecular immunology, Vol. 91, pp. 134-144, (2017) (PubMed).
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- 抗原
- IL17RA (Interleukin 17 Receptor A (IL17RA))
- 别名
- IL17RA (IL17RA 产品)
- 别名
- IL17R antibody, CANDF5 antibody, CD217 antibody, CDw217 antibody, IL-17RA antibody, hIL-17R antibody, Il17r antibody, AW538159 antibody, Cdw217 antibody, VDw217 antibody, interleukin 17 receptor A antibody, IL17RA antibody, Il17ra antibody
- 背景
- Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor, IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Alternative splicing results in multiple transcript variants encoding different isoforms.,IL17RA,CANDF5,CD217,CDw217,IL-17RA,IL17R,IMD51,hIL-17R,Immunology & Inflammation,CD markers,Cytokines,Interleukins,Cell Intrinsic Innate Immunity Signaling Pathway,IL17RA
- 分子量
- 92 kDa/96 kDa
- 基因ID
- 23765
- UniProt
- Q96F46
- 途径
- SARS-CoV-2 Protein Interactome
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