This gene is a member of the Antp homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded nuclear protein functions as a sequence-specific transcription factor that is involved in cell proliferation and differentiation. Increased expression of this gene is associated with some cases of melanoma and ovarian carcinoma.,HOXB7,HHO.C1,HOX2,HOX2C,Hox-2.3,Epigenetics & Nuclear Signaling,Transcription Factors,HOXB7