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- 抗原 See all GNA12 抗体
- GNA12 (Guanine Nucleotide Binding Protein (G Protein) alpha 12 (GNA12))
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抗原表位
- AA 1-200
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GNA12 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- MSGVVRTLSR CLLPAEAGGA RERRAGSGAR DAEREARRRS RDIDALLARE RRAVRRLVKI LLLGAGESGK STFLKQMRII HGREFDQKAL LEFRDTIFDN ILKGSRVLVD ARDKLGIPWQ YSENEKHGMF LMAFENKAGL PVEPATFQLY VPALSALWRD SGIREAFSRR SEFQLGESVK YFLDNLDRIG QLNYFPSKQD
- 交叉反应
- 人, 小鼠, 大鼠
- 产品特性
- Polyclonal Antibodies
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human GNA12 (NP_031379.2).
- 亚型
- IgG
- Top Product
- Discover our top product GNA12 Primary Antibody
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anti-Guanine Nucleotide Binding Protein (G Protein) alpha 12 (GNA12) (AA 112-270) antibody
GNA12 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Guanine Nucleotide Binding Protein (G Protein) alpha 12 (GNA12) (AA 301-381) antibodyGNA12 适用: 人 ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Guanine Nucleotide Binding Protein (G Protein) alpha 12 (GNA12) (C-Term) antibodyGNA12 适用: 人, 大鼠, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Guanine Nucleotide Binding Protein (G Protein) alpha 12 (GNA12) (Internal Region) antibodyVerified GNA12 适用: 人, 小鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Guanine Nucleotide Binding Protein (G Protein) alpha 12 (GNA12) (AA 146-195) antibodyGNA12 适用: 人, 大鼠, 小鼠, 犬, 豚鼠, 马, 兔, Cow, 斑马鱼, Hamster, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Guanine Nucleotide Binding Protein (G Protein) alpha 12 (GNA12) (Ser67) antibodyGNA12 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Guanine Nucleotide Binding Protein (G Protein) alpha 12 (GNA12) (Middle Region) antibodyGNA12 适用: 人, 大鼠, 小鼠, 犬, 豚鼠, 马, 兔, Cow, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- GNA12 (Guanine Nucleotide Binding Protein (G Protein) alpha 12 (GNA12))
- 别名
- GNA12 (GNA12 产品)
- 别名
- NNX3 antibody, RMP antibody, gep antibody, gna12 antibody, gna12l antibody, AI414047 antibody, AI504261 antibody, Galpha12 antibody, G protein subunit alpha 12 antibody, guanine nucleotide binding protein (G protein) alpha 12a antibody, guanine nucleotide binding protein, alpha 12 antibody, GNA12 antibody, Gna12 antibody, gna12a antibody
- 背景
- Guanine nucleotide-binding proteins (G proteins are involved as modulators or transducers in various transmembrane signaling systems. Activates effector molecule RhoA by binding and activating RhoGEFs (ARHGEF12/LARG. GNA12-dependent Rho signaling subsequently regulates transcription factor AP-1 (activating protein-1 (By similarity. GNA12-dependent Rho signaling also regulates protein phosphatese 2A activation causing dephosphorylation of its target proteins. Promotes tumor cell invasion and metastasis by activating RhoA/ROCK signaling pathway and up-regulating proinflammatory cytokine production. Inhibits CDH1-mediated cell adhesion in process independent from Rho activation. Together with NAPA promotes CDH5 localization to plasma membrane. May play a role in the control of cell migration through the TOR signaling cascade.,GNA12,NNX3,RMP,gep,Epigenetics & Nuclear Signaling,Translation Control,Regulation of eIF4 and p70 S6 Kinase,Signal Transduction,G protein signaling,mTOR Signaling Pathway,MAPK-JNK Signaling Pathway,GNA12
- 分子量
- 34 kDa/37 kDa/44 kDa
- 基因ID
- 2768
- UniProt
- Q03113
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