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Geminin 抗体 (AA 1-209)

GMNN 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6141186
发货至: 中国
  • 抗原 See all Geminin (GMNN) 抗体
    Geminin (GMNN) (Geminin, DNA Replication Inhibitor (GMNN))
    抗原表位
    • 8
    • 7
    • 6
    • 6
    • 6
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-209
    适用
    • 54
    • 11
    • 10
    宿主
    • 46
    • 10
    克隆类型
    • 44
    • 12
    多克隆
    标记
    • 31
    • 5
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Geminin antibody is un-conjugated
    应用范围
    • 31
    • 25
    • 24
    • 12
    • 8
    • 7
    • 7
    • 6
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    MNPSMKQKQE EIKENIKNSS VPRRTLKMIQ PSASGSLVGR ENELSAGLSK RKHRNDHLTS TTSSPGVIVP ESSENKNLGG VTQESFDLMI KENPSSQYWK EVAEKRRKAL YEALKENEKL HKEIEQKDNE IARLKKENKE LAEVAEHVQY MAELIERLNG EPLDNFESLD NQEFDSEEET VEDSLVEDSE IGTCAEGTVS SSTDAKPCI
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-209 of human GMNN (NP_056979.1).
    亚型
    IgG
    Top Product
    Discover our top product GMNN Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IHC,1:50 - 1:200
    说明

    HIGH QUALITY

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    Geminin (GMNN) (Geminin, DNA Replication Inhibitor (GMNN))
    别名
    GMNN (GMNN 产品)
    别名
    CG3183 antibody, Dm Geminin antibody, Dm geminin antibody, Dmel\\CG3183 antibody, Gem antibody, Geminin antibody, anon-WO0257455.1 antibody, gem antibody, l(2)k14019 antibody, v(2)k09107 antibody, sb:cb254 antibody, zgc:66217 antibody, GB16871 antibody, GMNN antibody, geminin antibody, dyak_GLEANR_833 antibody, DyakGE24654 antibody, GE24654 antibody, LOC100049517 antibody, AW546347 antibody, geminin, DNA replication inhibitor antibody, CG3183 gene product from transcript CG3183-RA antibody, geminin antibody, GE24654 gene product from transcript GE24654-RA antibody, GMNN antibody, geminin antibody, gmnn antibody, LOC410093 antibody, Dyak\geminin antibody, Gmnn antibody
    背景
    This gene encodes a protein that plays a critical role in cell cycle regulation. The encoded protein inhibits DNA replication by binding to DNA replication factor Cdt1, preventing the incorporation of minichromosome maintenance proteins into the pre-replication complex. The encoded protein is expressed during the S and G2 phases of the cell cycle and is degraded by the anaphase-promoting complex during the metaphase-anaphase transition. Increased expression of this gene may play a role in several malignancies including colon, rectal and breast cancer. Alternatively spliced transcript variants have been observed for this gene, and two pseudogenes of this gene are located on the short arm of chromosome 16.,GMNN,Gem,MGORS6,geminin,Epigenetics & Nuclear Signaling,Cancer,Cell Biology & Developmental Biology,Cell Cycle,GMNN
    分子量
    23 kDa
    基因ID
    51053
    UniProt
    O75496
    途径
    EGFR Signaling Pathway, DNA Replication
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