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- 抗原 See all GLI1 抗体
- GLI1 (Zinc Finger Protein GLI1 (GLI1))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GLI1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 交叉反应
- 人, 小鼠, 大鼠
- 产品特性
- Polyclonal Antibodies
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant protein of human GLI1
- 亚型
- IgG
- Top Product
- Discover our top product GLI1 Primary Antibody
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- 应用备注
- WB,1:500 - 1:2000
- 说明
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HIGH QUALITY
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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Disulfiram/copper targets stem cell-like ALDH+ population of multiple myeloma by inhibition of ALDH1A1 and Hedgehog pathway." in: Journal of cellular biochemistry, Vol. 119, Issue 8, pp. 6882-6893, (2018) (PubMed).
: "Exendin-4 promotes the osteogenic differentiation of osteoblasts via the Hedgehog/Gli1 signaling pathway." in: American journal of translational research, Vol. 10, Issue 1, pp. 315-324, (2018) (PubMed).
: "Arsenic trioxide inhibits cancer stem-like cells via down-regulation of Gli1 in lung cancer." in: American journal of translational research, Vol. 8, Issue 2, pp. 1133-43, (2016) (PubMed).
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Disulfiram/copper targets stem cell-like ALDH+ population of multiple myeloma by inhibition of ALDH1A1 and Hedgehog pathway." in: Journal of cellular biochemistry, Vol. 119, Issue 8, pp. 6882-6893, (2018) (PubMed).
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- 抗原
- GLI1 (Zinc Finger Protein GLI1 (GLI1))
- 别名
- GLI1 (GLI1 产品)
- 别名
- GLI antibody, Gli antibody, Gli-1 antibody, gli1.1 antibody, AV235269 antibody, Zfp-5 antibody, Zfp5 antibody, GLI family zinc finger 1 antibody, GLI family zinc finger 1 S homeolog antibody, GLI-Kruppel family member GLI1 antibody, GLI1 antibody, Gli1 antibody, gli1.S antibody, gli1 antibody
- 背景
- This gene encodes a member of the Kruppel family of zinc finger proteins. The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation. The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop. Multiple transcript variants encoding different isoforms have been found for this gene.,GLI1,GLI,Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,Tumor suppressors,Signal Transduction,Cell Biology & Developmental Biology,Hedgehog Signaling Pathway,Neuroscience,Stem Cells,GLI1
- 分子量
- 104 kDa/113 kDa/117 kDa
- 基因ID
- 2735
- UniProt
- P08151
- 途径
- Hedgehog Signaling, Dopaminergic Neurogenesis
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