GALE 抗体 (AA 129-348)
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- 抗原 See all GALE 抗体
- GALE (UDP-Galactose-4-Epimerase (GALE))
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抗原表位
- AA 129-348
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GALE antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- FSSSATVYGN PQYLPLDEAH PTGGCTNPYG KSKFFIEEMI RDLCQADKTW NAVLLRYFNP TGAHASGCIG EDPQGIPNNL MPYVSQVAIG RREALNVFGN DYDTEDGTGV RDYIHVVDLA KGHIAALRKL KEQCGCRIYN LGTGTGYSVL QMVQAMEKAS GKKIPYKVVA RREGDVAACY ANPSLAQEEL GWTAALGLDR MCEDLWRWQK QNPSGFGTQA
- 交叉反应
- 人, 小鼠, 大鼠
- 产品特性
- Polyclonal Antibodies
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 129-348 of human GALE (NP_001121093.1).
- 亚型
- IgG
- Top Product
- Discover our top product GALE Primary Antibody
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- 应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
- 说明
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HIGH QUALITY
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- GALE (UDP-Galactose-4-Epimerase (GALE))
- 别名
- GALE (GALE 产品)
- 背景
- This gene encodes UDP-galactose-4-epimerase which catalyzes two distinct but analogous reactions: the epimerization of UDP-glucose to UDP-galactose, and the epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The bifunctional nature of the enzyme has the important metabolic consequence that mutant cells (or individuals) are dependent not only on exogenous galactose, but also on exogenous N-acetylgalactosamine as a necessary precursor for the synthesis of glycoproteins and glycolipids. Mutations in this gene result in epimerase-deficiency galactosemia, also referred to as galactosemia type 3, a disease characterized by liver damage, early-onset cataracts, deafness and mental retardation, with symptoms ranging from mild ('peripheral' form) to severe ('generalized' form). Multiple alternatively spliced transcripts encoding the same protein have been identified.,GALE,SDR1E1,Cancer,Signal Transduction,Endocrine & Metabolism,Carbohydrate metabolism,GALE
- 分子量
- 30 kDa/38 kDa
- 基因ID
- 2582
- UniProt
- Q14376
- 途径
- Response to Water Deprivation, Cellular Glucan Metabolic Process
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