AW743446 antibody, mKIAA1752 antibody, RGD1305121 antibody, FTO, alpha-ketoglutarate dependent dioxygenase antibody, fat mass and obesity associated antibody, fat mass and obesity associated L homeolog antibody, FTO antibody, Fto antibody, fto.L antibody
背景
This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes.,FTO,ALKBH9,BMIQ14,GDFD,Epigenetics & Nuclear Signaling,Cancer,Endocrine & Metabolism,Lipid Metabolism,Endocrine and metabolic diseases,Diabetes,Metabolic disorders,Obesity,Neuroscience,Cardiovascular,Heart,Cardiovascular diseases,Heart disease,FTO