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FKBP4 抗体 (AA 220-459)

FKBP4 适用: 人 WB, IHC, IP, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6140658
发货至: 中国
  • 抗原 See all FKBP4 抗体
    FKBP4 (FK506 Binding Protein 4, 59kDa (FKBP4))
    抗原表位
    • 15
    • 7
    • 7
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 220-459
    适用
    • 100
    • 32
    • 16
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 2
    • 1
    • 1
    宿主
    • 62
    • 36
    • 2
    克隆类型
    • 58
    • 42
    多克隆
    标记
    • 46
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FKBP4 antibody is un-conjugated
    应用范围
    • 82
    • 48
    • 37
    • 26
    • 19
    • 16
    • 15
    • 15
    • 14
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)
    序列
    YLKPSYAFGS VGKEKFQIPP NAELKYELHL KSFEKAKESW EMNSEEKLEQ STIVKERGTV YFKEGKYKQA LLQYKKIVSW LEYESSFSNE EAQKAQALRL ASHLNLAMCH LKLQAFSAAI ESCNKALELD SNNEKGLFRR GEAHLAVNDF ELARADFQKV LQLYPNNKAA KTQLAVCQQR IRRQLAREKK LYANMFERLA EEENKAKAEA SSGDHPTDTE MKEEQKSNTA GSQSQVETEA
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 220-459 of human FKBP52/FKBP52/FKBP4 (NP_002005.1).
    亚型
    IgG
    Top Product
    Discover our top product FKBP4 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:100,IP,1:50 - 1:200
    说明

    HIGH QUALITY

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    FKBP4 (FK506 Binding Protein 4, 59kDa (FKBP4))
    别名
    FKBP4 (FKBP4 产品)
    别名
    HBI antibody, p52 antibody, hsp56 antibody, PPIase antibody, fkbp52 antibody, fkbp59 antibody, MGC81078 antibody, wu:fb34f09 antibody, 59kDa antibody, AL022792 antibody, AW208983 antibody, FKBP-4 antibody, FKBP-52 antibody, FKBP52 antibody, FKPB52 antibody, p59 antibody, FKBP51 antibody, FKBP59 antibody, Hsp56 antibody, P59 antibody, FK506 binding protein 4 antibody, FK506 binding protein 4 S homeolog antibody, FKBP4 antibody, fkbp4.S antibody, fkbp4 antibody, Fkbp4 antibody
    背景
    The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It has high structural and functional similarity to FK506-binding protein 1A (FKBP1A), but unlike FKBP1A, this protein does not have immunosuppressant activity when complexed with FK506. It interacts with interferon regulatory factor-4 and plays an important role in immunoregulatory gene expression in B and T lymphocytes. This encoded protein is known to associate with phytanoyl-CoA alpha-hydroxylase. It can also associate with two heat shock proteins (hsp90 and hsp70) and thus may play a role in the intracellular trafficking of hetero-oligomeric forms of the steroid hormone receptors. This protein correlates strongly with adeno-associated virus type 2 vectors (AAV) resulting in a significant increase in AAV-mediated transgene expression in human cell lines. Thus this encoded protein is thought to have important implications for the optimal use of AAV vectors in human gene therapy. The human genome contains several non-transcribed pseudogenes similar to this gene.,FKBP4,FKBP51,FKBP52,FKBP59,HBI,Hsp56,PPIase,p52,Epigenetics & Nuclear Signaling,RNA Binding,Nuclear Receptor Signaling,Nuclear hormone receptors,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Microtubules,FKBP4
    分子量
    51 kDa
    基因ID
    2288
    UniProt
    Q02790
    途径
    Intracellular Steroid Hormone Receptor Signaling Pathway
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