FKBP4 抗体 (AA 220-459)
-
- 抗原 See all FKBP4 抗体
- FKBP4 (FK506 Binding Protein 4, 59kDa (FKBP4))
-
抗原表位
- AA 220-459
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This FKBP4 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)
- 序列
- YLKPSYAFGS VGKEKFQIPP NAELKYELHL KSFEKAKESW EMNSEEKLEQ STIVKERGTV YFKEGKYKQA LLQYKKIVSW LEYESSFSNE EAQKAQALRL ASHLNLAMCH LKLQAFSAAI ESCNKALELD SNNEKGLFRR GEAHLAVNDF ELARADFQKV LQLYPNNKAA KTQLAVCQQR IRRQLAREKK LYANMFERLA EEENKAKAEA SSGDHPTDTE MKEEQKSNTA GSQSQVETEA
- 交叉反应
- 人, 小鼠, 大鼠
- 产品特性
- Polyclonal Antibodies
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 220-459 of human FKBP52/FKBP52/FKBP4 (NP_002005.1).
- 亚型
- IgG
- Top Product
- Discover our top product FKBP4 Primary Antibody
-
-
- 应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:100,IP,1:50 - 1:200
- 说明
-
HIGH QUALITY
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
-
- 抗原
- FKBP4 (FK506 Binding Protein 4, 59kDa (FKBP4))
- 别名
- FKBP4 (FKBP4 产品)
- 别名
- HBI antibody, p52 antibody, hsp56 antibody, PPIase antibody, fkbp52 antibody, fkbp59 antibody, MGC81078 antibody, wu:fb34f09 antibody, 59kDa antibody, AL022792 antibody, AW208983 antibody, FKBP-4 antibody, FKBP-52 antibody, FKBP52 antibody, FKPB52 antibody, p59 antibody, FKBP51 antibody, FKBP59 antibody, Hsp56 antibody, P59 antibody, FK506 binding protein 4 antibody, FK506 binding protein 4 S homeolog antibody, FKBP4 antibody, fkbp4.S antibody, fkbp4 antibody, Fkbp4 antibody
- 背景
- The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It has high structural and functional similarity to FK506-binding protein 1A (FKBP1A), but unlike FKBP1A, this protein does not have immunosuppressant activity when complexed with FK506. It interacts with interferon regulatory factor-4 and plays an important role in immunoregulatory gene expression in B and T lymphocytes. This encoded protein is known to associate with phytanoyl-CoA alpha-hydroxylase. It can also associate with two heat shock proteins (hsp90 and hsp70) and thus may play a role in the intracellular trafficking of hetero-oligomeric forms of the steroid hormone receptors. This protein correlates strongly with adeno-associated virus type 2 vectors (AAV) resulting in a significant increase in AAV-mediated transgene expression in human cell lines. Thus this encoded protein is thought to have important implications for the optimal use of AAV vectors in human gene therapy. The human genome contains several non-transcribed pseudogenes similar to this gene.,FKBP4,FKBP51,FKBP52,FKBP59,HBI,Hsp56,PPIase,p52,Epigenetics & Nuclear Signaling,RNA Binding,Nuclear Receptor Signaling,Nuclear hormone receptors,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Microtubules,FKBP4
- 分子量
- 51 kDa
- 基因ID
- 2288
- UniProt
- Q02790
- 途径
- Intracellular Steroid Hormone Receptor Signaling Pathway
-