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- 抗原 See all FGD4 抗体
- FGD4 (FYVE, RhoGEF and PH Domain Containing 4 (FGD4))
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抗原表位
- AA 99-198
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FGD4 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- QMECEEEKAA TLSSDTSIQA SEPLLDTHIV NGERDETATA PASPTTDSCD GNASDSSYRT PGIGPVLPLE ERGAETETKV QERENGESPL ELEQLDQHHE
- 交叉反应
- 人, 小鼠, 大鼠
- 产品特性
- Polyclonal Antibodies
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 99-198 of human FGD4 (NP_640334.2).
- 亚型
- IgG
- Top Product
- Discover our top product FGD4 Primary Antibody
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anti-FYVE, RhoGEF and PH Domain Containing 4 (FGD4) antibody
FGD4 适用: 人 WB, IHC (p), ICC, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB,1:500 - 1:2000
- 说明
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HIGH QUALITY
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- FGD4 (FYVE, RhoGEF and PH Domain Containing 4 (FGD4))
- 别名
- FGD4 (FGD4 产品)
- 别名
- CMT4H antibody, FRABP antibody, ZFYVE6 antibody, 9030023J02Rik antibody, 9330209B17Rik antibody, Frabp antibody, FYVE, RhoGEF and PH domain containing 4 antibody, FGD4 antibody, Fgd4 antibody
- 背景
- This gene encodes a protein that is involved in the regulation of the actin cytoskeleton and cell shape. This protein contains an actin filament-binding domain, which together with its Dbl homology domain and one of its pleckstrin homology domains, can form microspikes. This protein can activate MAPK8 independently of the actin filament-binding domain, and it is also involved in the activation of CDC42 via the exchange of bound GDP for free GTP. The activation of CDC42 also enables this protein to play a role in mediating the cellular invasion of Cryptosporidium parvum, an intracellular parasite that infects the gastrointestinal tract. Mutations in this gene can cause Charcot-Marie-Tooth disease type 4H (CMT4H), a disorder of the peripheral nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.,FGD4,CMT4H,FRABP,ZFYVE6,FYVE,FGD4
- 分子量
- 20 kDa/32 kDa/86 kDa
- 基因ID
- 121512
- UniProt
- Q96M96
- 途径
- Neurotrophin Signaling Pathway
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