FERMT2 抗体 (AA 380-550)
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- 抗原 See all FERMT2 抗体
- FERMT2 (Fermitin Family Member 2 (FERMT2))
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抗原表位
- AA 380-550
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FERMT2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- KVFKPKKLTL KGYKQYWCTF KDTSISCYKS KEESSGTPAH QMNLRGCEVT PDVNISGQKF NIKLLIPVAE GMNEIWLRCD NEKQYAHWMA ACRLASKGKT MADSSYNLEV QNILSFLKMQ HLNPDPQLIP EQITTDITPE CLVSPRYLKK YKNKQITARI LEAHQNVAQM S
- 交叉反应
- 人, 小鼠, 大鼠
- 产品特性
- Polyclonal Antibodies
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 380-550 of human FERMT2 (NP_006823.1).
- 亚型
- IgG
- Top Product
- Discover our top product FERMT2 Primary Antibody
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- 应用备注
- WB,1:1000 - 1:2000,IHC,1:50 - 1:200
- 说明
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HIGH QUALITY
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- FERMT2 (Fermitin Family Member 2 (FERMT2))
- 别名
- FERMT2 (FERMT2 产品)
- 别名
- AA960555 antibody, Kindlin-2 antibody, Mig2 antibody, Plekhc1 antibody, KIND2 antibody, MIG2 antibody, PLEKHC1 antibody, UNC112 antibody, UNC112B antibody, mig-2 antibody, fermitin family member 2 antibody, Fermt2 antibody, FERMT2 antibody
- 背景
- Scaffolding protein that enhances integrin activation mediated by TLN1 and/or TLN2, but activates integrins only weakly by itself. Binds to membranes enriched in phosphoinositides. Enhances integrin-mediated cell adhesion onto the extracellular matrix and cell spreading, this requires both its ability to interact with integrins and with phospholipid membranes. Required for the assembly of focal adhesions. Participates in the connection between extracellular matrix adhesion sites and the actin cytoskeleton and also in the orchestration of actin assembly and cell shape modulation. Recruits FBLIM1 to focal adhesions. Plays a role in the TGFB1 and integrin signaling pathways. Stabilizes active CTNNB1 and plays a role in the regulation of transcription mediated by CTNNB1 and TCF7L2/TCF4 and in Wnt signaling.,FERMT2,KIND2,MIG2,PLEKHC1,UNC112,UNC112B,mig-2,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Cytoskeleton,Stem Cells,Mesenchymal Stem Cells,FERMT2
- 分子量
- 72 kDa/77 kDa/78 kDa
- 基因ID
- 10979
- UniProt
- Q96AC1
- 途径
- Cell-Cell Junction Organization
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