FBL2 antibody, FBL3 antibody, 2810423A21Rik antibody, Fbl3 antibody, RGD1562243 antibody, fbxl20 antibody, sb:cb783 antibody, zgc:73374 antibody, Fbl2 antibody, Fbxl2 antibody, F-box and leucine rich repeat protein 2 antibody, F-box and leucine-rich repeat protein 2 antibody, F-box and leucine-rich repeat protein 20 antibody, FBXL2 antibody, Fbxl2 antibody, fbxl2 antibody, Fbxl20 antibody
背景
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains 12 tandem leucine-rich repeats. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,FBXL2,FBL2,FBL3,FBXL2