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EIF3E 抗体 (AA 1-445)

EIF3E 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6140059
发货至: 中国
  • 抗原 See all EIF3E 抗体
    EIF3E (Eukaryotic Translation Initiation Factor 3 Subunit E (EIF3E))
    抗原表位
    • 7
    • 6
    • 6
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-445
    适用
    • 44
    • 23
    • 19
    • 7
    • 7
    • 6
    • 6
    • 6
    • 6
    • 3
    • 3
    • 2
    • 1
    • 1
    宿主
    • 42
    • 1
    • 1
    克隆类型
    • 43
    • 1
    多克隆
    标记
    • 27
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This EIF3E antibody is un-conjugated
    应用范围
    • 35
    • 19
    • 7
    • 7
    • 6
    • 4
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    MAEYDLTTRI AHFLDRHLVF PLLEFLSVKE IYNEKELLQG KLDLLSDTNM VDFAMDVYKN LYSDDIPHAL REKRTTVVAQ LKQLQAETEP IVKMFEDPET TRQMQSTRDG RMLFDYLADK HGFRQEYLDT LYRYAKFQYE CGNYSGAAEY LYFFRVLVPA TDRNALSSLW GKLASEILMQ NWDAAMEDLT RLKETIDNNS VSSPLQSLQQ RTWLIHWSLF VFFNHPKGRD NIIDLFLYQP QYLNAIQTMC PHILRYLTTA VITNKDVRKR RQVLKDLVKV IQQESYTYKD PITEFVECLY VNFDFDGAQK KLRECESVLV NDFFLVACLE DFIENARLFI FETFCRIHQC ISINMLADKL NMTPEEAERW IVNLIRNARL DAKIDSKLGH VVMGNNAVSP YQQVIEKTKS LSFRSQMLAM NIEKKLNQNS RSEAPNWATQ DSGFY
    交叉反应
    人, 小鼠
    产品特性
    Polyclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-445 of human eIF3e (NP_001559.1).
    亚型
    IgG
    Top Product
    Discover our top product EIF3E Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000
    说明

    HIGH QUALITY

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    EIF3E (Eukaryotic Translation Initiation Factor 3 Subunit E (EIF3E))
    别名
    EIF3E (EIF3E 产品)
    别名
    EIF3-P48 antibody, EIF3S6 antibody, INT6 antibody, eIF3-p46 antibody, 48kDa antibody, Eif3s6 antibody, Int6 antibody, eIF3-p48 antibody, eif3-p48 antibody, eif3s6 antibody, eif3s6-A antibody, eIF3e antibody, eIF3-S6 antibody, eif3s6-B antibody, EIF3SE antibody, eif3s6b antibody, im:7147439 antibody, QtsA-18056 antibody, eukaryotic translation initiation factor 3 subunit E antibody, eukaryotic translation initiation factor 3, subunit E antibody, eukaryotic translation initiation factor 3 subunit E L homeolog antibody, eukaryotic translation initiation factor 3 subunit 6 antibody, eukaryotic translation initiation factor 3 subunit E S homeolog antibody, eukaryotic translation initiation factor 3, subunit E, a antibody, Eukaryotic translation initiation factor 3 subunit E antibody, eukaryotic translation initiation factor 3, subunit E, b antibody, EIF3E antibody, Eif3e antibody, eif3e antibody, eif3e.L antibody, LOC692936 antibody, eif3e.S antibody, eif3ea antibody, eif-3.E antibody, eif3eb antibody, LOC108348260 antibody, int6 antibody
    背景
    Component of the eukaryotic translation initiation factor 3 (eIF-3 complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC. The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression. Required for nonsense-mediated mRNA decay (NMD, may act in conjunction with UPF2 to divert mRNAs from translation to the NMD pathway. May interact with MCM7 and EPAS1 and regulate the proteasome-mediated degradation of these proteins.,EIF3E,EIF3-P48,EIF3S6,INT6,eIF3-p46,Epigenetics & Nuclear Signaling,EIF3E
    分子量
    52 kDa
    基因ID
    3646
    UniProt
    P60228
    途径
    Ribonucleoprotein Complex Subunit Organization, Hepatitis C
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