EIF3C 抗体 (AA 694-913)
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- 抗原 See all EIF3C 抗体
- EIF3C (Eukaryotic Translation Initiation Factor 3 Subunit C (EIF3C))
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抗原表位
- AA 694-913
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This EIF3C antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- 序列
- EIPYMAAHES DARRRMISKQ FHHQLRVGER QPLLGPPESM REHVVAASKA MKMGDWKTCH SFIINEKMNG KVWDLFPEAD KVRTMLVRKI QEESLRTYLF TYSSVYDSIS METLSDMFEL DLPTVHSIIS KMIINEELMA SLDQPTQTVV MHRTEPTAQQ NLALQLAEKL GSLVENNERV FDHKQGTYGG YFRDQKDGYR KNEGYMRRGG YRQQQSQTAY
- 交叉反应
- 人, 小鼠, 大鼠
- 产品特性
- Polyclonal Antibodies
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 694-913 of human EIF3C (NP_003743.1).
- 亚型
- IgG
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- 应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:100
- 说明
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HIGH QUALITY
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- EIF3C (Eukaryotic Translation Initiation Factor 3 Subunit C (EIF3C))
- 别名
- EIF3C (EIF3C 产品)
- 别名
- eif3s8 antibody, fi37c04 antibody, zgc:66128 antibody, wu:fb34a08 antibody, wu:fi37c04 antibody, EIF3S8 antibody, EIF3CL antibody, eif3-p110 antibody, LOC733086 antibody, eIF3c antibody, eIF3-S8 antibody, AO090011000340 antibody, eIF3-p110 antibody, 110kDa antibody, 3230401O13Rik antibody, Eif3s8 antibody, NIPIL(A3) antibody, NipilA3 antibody, Xs antibody, Xsl antibody, EIF3C antibody, eukaryotic translation initiation factor 3, subunit C antibody, eukaryotic translation initiation factor 3 subunit C antibody, eukaryotic translation initiation factor 3 subunit 8 antibody, Eukaryotic translation initiation factor 3 subunit C antibody, translation initiation factor eIF3c antibody, translation initiation factor eIF-3 subunit 8 antibody, eukaryotic translation initiation factor 3 subunit C L homeolog antibody, eukaryotic translation initiation factor 3, subunit C-like antibody, eif3c antibody, LOC454016 antibody, LOC479795 antibody, EIF3C antibody, Smp_000480 antibody, eIF3c antibody, ANI_1_1094124 antibody, AOR_1_578054 antibody, PTRG_08272 antibody, SJAG_04981 antibody, TERG_03202 antibody, PGTG_09255 antibody, Tsp_05110 antibody, Eif3c antibody, eif3c.L antibody, EIF3CL antibody, eif-3.C antibody
- 背景
- Component of the eukaryotic translation initiation factor 3 (eIF-3 complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC. The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.,EIF3C,EIF3CL,EIF3S8,eIF3-p110,Epigenetics & Nuclear Signaling,RNA Binding,Translation Control,EIF3C
- 分子量
- 104 kDa/105 kDa
- 基因ID
- 8663
- UniProt
- Q99613
- 途径
- Ribonucleoprotein Complex Subunit Organization
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