C20orf180 antibody, 2700055C10Rik antibody, RGD1562846 antibody, docking protein 5 antibody, Docking protein 5 antibody, DOK5 antibody, dok5 antibody, Dok5 antibody
背景
The protein encoded by this gene is a member of the DOK family of membrane proteins, which are adapter proteins involved in signal transduction. The encoded protein interacts with phosphorylated receptor tyrosine kinases to mediate neurite outgrowth and activation of the MAP kinase pathway. Unlike other DOK family proteins, this protein does not interact with RASGAP. This protein is up-regulated in patients with systemic sclerosis and is associated with fibrosis induced by insulin-like growth factor binding protein 5. Alternative splicing of this gene results in multiple transcript variants.,DOK5,C20orf180,IRS-6,IRS6,Signal Transduction,Kinase,Tyrosine kinases,DOK5