This gene encodes a member of the membrane fatty acid desaturase family which is responsible for inserting double bonds into specific positions in fatty acids. This protein contains three His-containing consensus motifs that are characteristic of a group of membrane fatty acid desaturases. It is predicted to be a multiple membrane-spanning protein localized to the endoplasmic reticulum. Overexpression of this gene inhibited biosynthesis of the EGF receptor, suggesting a possible role of a fatty acid desaturase in regulating biosynthetic processing of the EGF receptor.,DEGS1,DEGS,DEGS-1,DES1,Des-1,FADS7,MIG15,MLD,Cancer,Endocrine & Metabolism,Lipid Metabolism,Cardiovascular,Lipids,Fatty Acids,DEGS1