Casein Kinase 1 gamma 2 抗体 (AA 316-415)
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- 抗原 See all Casein Kinase 1 gamma 2 (CSNK1G2) 抗体
- Casein Kinase 1 gamma 2 (CSNK1G2) (Casein Kinase 1, gamma 2 (CSNK1G2))
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抗原表位
- AA 316-415
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Casein Kinase 1 gamma 2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- FDRSGFVFDY EYDWAGKPLP TPIGTVHTDL PSQPQLRDKT QPHSKNQALN STNGELNADD PTAGHSNAPI TAPAEVEVAD ETKCCCFFKR RKRKSLQRHK
- 交叉反应
- 人, 小鼠, 大鼠
- 产品特性
- Polyclonal Antibodies
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 316-415 of human CSNK1G2 (NP_001310.3).
- 亚型
- IgG
- Top Product
- Discover our top product CSNK1G2 Primary Antibody
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- 应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
- 说明
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HIGH QUALITY
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- Casein Kinase 1 gamma 2 (CSNK1G2) (Casein Kinase 1, gamma 2 (CSNK1G2))
- 别名
- CSNK1G2 (CSNK1G2 产品)
- 别名
- CK1g2 antibody, 2810429I12Rik antibody, AI463719 antibody, CKI antibody, ck1-gamma antibody, CSNK1G2 antibody, ck1g2 antibody, csnk1g2 antibody, fj97g11 antibody, wu:fj97g11 antibody, wz8345 antibody, zgc:110719 antibody, zgc:153415 antibody, casein kinase 1 gamma 2 antibody, casein kinase 1, gamma 2 antibody, casein kinase 1 gamma 2 L homeolog antibody, casein kinase 1, gamma 2a antibody, casein kinase 1, gamma 2b antibody, CSNK1G2 antibody, Csnk1g2 antibody, csnk1g2.L antibody, csnk1g2 antibody, csnk1g2a antibody, csnk1g2b antibody
- 背景
- Serine/threonine-protein kinase. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates COL4A3BP/CERT, MTA1 and SMAD3. Involved in brain development and vesicular trafficking and neurotransmitter releasing from small synaptic vesicles. Regulates fast synaptic transmission mediated by glutamate. SMAD3 phosphorylation promotes its ligand-dependent ubiquitination and subsequent proteasome degradation, thus inhibiting SMAD3-mediated TGF-beta responses. Hyperphosphorylation of the serine-repeat motif of COL4A3BP/CERT leads to its inactivation by dissociation from the Golgi complex, thus down-regulating ER-to-Golgi transport of ceramide and sphingomyelin synthesis. Triggers PER1 proteasomal degradation probably through phosphorylation.,CSNK1G2,CK1g2,Cancer,Signal Transduction,Kinase,Endocrine & Metabolism,Lipid Metabolism,Stem Cells,CSNK1G2
- 分子量
- 47 kDa
- 基因ID
- 1455
- UniProt
- P78368
- 途径
- Hedgehog Signaling
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