EFCAB4B 抗体 (AA 1-200)
Quick Overview for EFCAB4B 抗体 (AA 1-200) (ABIN6138999)
抗原
See all EFCAB4B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-200
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序列
- MAAPDGRVVS RPQRLGQGSG QGPKGSGACL HPLDSLEQKE TQEQTSGQLV MLRKAQEFFQ TCDAEGKGFI ARKDMQRLHK ELPLSLEELE DVFDALDADG NGYLTPQEFT TGFSHFFFSQ NNPSQEDAGE QVAQRHEEKV YLSRGDEDLG DMGEDEEAQF RMLMDRLGAQ KVLEDESDVK QLWLQLKKEE PHLLSNFEDF
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交叉反应
- 人, 小鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human CRACR2A (NP_001138430.1).
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亚型
- IgG
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anti-EF-Hand Calcium Binding Domain 4B (EFCAB4B) (AA 1-395) antibody
EFCAB4B 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-EF-Hand Calcium Binding Domain 4B (EFCAB4B) (AA 215-264) antibodyEFCAB4B 适用: 人, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-EF-Hand Calcium Binding Domain 4B (EFCAB4B) (AA 71-120) antibodyEFCAB4B 适用: 人, 马, 大鼠, Cow, 犬, 豚鼠, 兔 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- EFCAB4B (EF-Hand Calcium Binding Domain 4B (EFCAB4B))
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别名
- CRACR2A
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背景
- [Isoform 1]: Ca(2+-binding protein that plays a key role in store-operated Ca(2+ entry (SOCE in T-cells by regulating CRAC channel activation. Acts as a cytoplasmic calcium-sensor that facilitates the clustering of ORAI1 and STIM1 at the junctional regions between the plasma membrane and the endoplasmic reticulum upon low Ca(2+ concentration. It thereby regulates CRAC channel activation, including translocation and clustering of ORAI1 and STIM1. Upon increase of cytoplasmic Ca(2+ resulting from opening of CRAC channels, dissociates from ORAI1 and STIM1, thereby destabilizing the ORAI1-STIM1 complex.,CRACR2A,EFCAB4B,Signal Transduction,Neuroscience,Calcium Signaling,CRACR2A
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分子量
- 45 kDa/83 kDa
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基因ID
- 84766
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UniProt
- Q9BSW2
抗原
-
