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CD35 抗体 (AA 420-550)

CR1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6138990
发货至: 中国
  • 抗原 See all CD35 (CR1) 抗体
    CD35 (CR1) (Complement Component Receptor 1 (CD35) (CR1))
    抗原表位
    • 15
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 420-550
    适用
    • 103
    • 25
    • 20
    • 16
    • 16
    • 15
    • 15
    • 4
    • 3
    宿主
    • 65
    • 39
    • 1
    克隆类型
    • 70
    • 32
    • 3
    多克隆
    标记
    • 41
    • 11
    • 8
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD35 antibody is un-conjugated
    应用范围
    • 63
    • 31
    • 27
    • 26
    • 20
    • 18
    • 16
    • 14
    • 14
    • 13
    • 13
    • 11
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    序列
    FCPSPPVIPN GRHTGKPLEV FPFGKTVNYT CDPHPDRGTS FDLIGESTIR CTSDPQGNGV WSSPAPRCGI LGHCQAPDHF LFAKLKTQTN ASDFPIGTSL KYECRPEYYG RPFSITCLDN LVWSSPKDVC K
    交叉反应
    产品特性
    Polyclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 420-550 of human CD35/CD35/CR1 (NP_000642.3).
    亚型
    IgG
    Top Product
    Discover our top product CR1 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IF,1:50 - 1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    CD35 (CR1) (Complement Component Receptor 1 (CD35) (CR1))
    别名
    CR1 (CR1 产品)
    别名
    C3BR antibody, C4BR antibody, CD35 antibody, KN antibody, C3DR antibody, CD21 antibody, Cr-1 antibody, Cr-2 antibody, Cr1 antibody, CR1-L antibody, CR2 antibody, CR1 antibody, complement C3b/C4b receptor 1 (Knops blood group) antibody, complement receptor 2 antibody, complement component (3d/Epstein Barr virus) receptor 2 antibody, complement receptor type 1 antibody, CR1 antibody, Cr2 antibody, CR2 antibody, LOC718120 antibody
    背景
    This gene is a member of the receptors of complement activation (RCA) family and is located in the 'cluster RCA' region of chromosome 1. The gene encodes a monomeric single-pass type I membrane glycoprotein found on erythrocytes, leukocytes, glomerular podocytes, and splenic follicular dendritic cells. The Knops blood group system is a system of antigens located on this protein. The protein mediates cellular binding to particles and immune complexes that have activated complement. Decreases in expression of this protein and/or mutations in its gene have been associated with gallbladder carcinomas, mesangiocapillary glomerulonephritis, systemic lupus erythematosus and sarcoidosis. Mutations in this gene have also been associated with a reduction in Plasmodium falciparum rosetting, conferring protection against severe malaria. Alternate allele-specific splice variants, encoding different isoforms, have been characterized. Additional allele specific isoforms, including a secreted form, have been described but have not been fully characterized.,CR1,C3BR,C4BR,CD35,KN,Immunology & Inflammation,CD markers,Stem Cells,Hematopoietic Progenitors,CR1
    分子量
    223 kDa
    基因ID
    1378
    UniProt
    P17927
    途径
    Complement System, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Endopeptidase Activity
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