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CPT1A 抗体 (AA 497-756)

CPT1A 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6138976
发货至: 中国
  • 抗原 See all CPT1A 抗体
    CPT1A (Carnitine Palmitoyltransferase 1A (Liver) (CPT1A))
    抗原表位
    • 10
    • 8
    • 6
    • 6
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 497-756
    适用
    • 45
    • 17
    • 15
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 56
    • 4
    • 2
    克隆类型
    • 57
    • 5
    多克隆
    标记
    • 29
    • 12
    • 10
    • 5
    • 3
    • 3
    This CPT1A antibody is un-conjugated
    应用范围
    • 57
    • 37
    • 21
    • 6
    • 6
    • 5
    • 5
    • 5
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF)
    序列
    GYAEDGHCKG DINPNIPYPT RLQWDIPGEC QEVIETSLNT ANLLANDVDF HSFPFVAFGK GIIKKCRTSP DAFVQLALQL AHYKDMGKFC LTYEASMTRL FREGRTETVR SCTTESCDFV RAMVDPAQTV EQRLKLFKLA SEKHQHMYRL AMTGSGIDRH LFCLYVVSKY LAVESPFLKE VLSEPWRLST SQTPQQQVEL FDLENNPEYV SSGGGFGPVA DDGYGVSYIL VGENLINFHI SSKFSCPETG IISQGPSSDT
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 497-756 of human CPT1A (NP_001027017.1).
    亚型
    IgG
  • 应用备注
    WB,1:500 - 1:2000,IF,1:50 - 1:200,IP,1:50 - 1:100
    说明

    HIGH QUALITY

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • Yang, He, Yao, Tan, Zhu, Li, Guo, Wei: "Regulation of AMPK-related glycolipid metabolism imbalances redox homeostasis and inhibits anchorage independent growth in human breast cancer cells." in: Redox biology, Vol. 17, pp. 180-191, (2018) (PubMed).

    Ni, He, Dai, Yao, Guo, Wei: "Oroxylin A suppresses the development and growth of colorectal cancer through reprogram of HIF1α-modulated fatty acid metabolism." in: Cell death & disease, Vol. 8, Issue 6, pp. e2865, (2018) (PubMed).

  • 抗原
    CPT1A (Carnitine Palmitoyltransferase 1A (Liver) (CPT1A))
    别名
    CPT1A (CPT1A 产品)
    别名
    MGC53498 antibody, CPT1 antibody, CPT1-L antibody, L-CPT1 antibody, L-CPTI antibody, si:dkey-56p7.8 antibody, C730027G07 antibody, CPTI antibody, Cpt1 antibody, CPT-Ia antibody, carnitine palmitoyltransferase 1A (liver) L homeolog antibody, carnitine palmitoyltransferase 1A antibody, carnitine palmitoyltransferase 1A (liver) antibody, carnitine palmitoyltransferase 1Aa (liver) antibody, carnitine palmitoyltransferase 1a, liver antibody, cpt1a.L antibody, CPT1A antibody, cpt1a antibody, cpt1aa antibody, Cpt1a antibody
    背景
    The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,CPT1A,CPT1,CPT1-L,L-CPT1,Cancer,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Lipid Metabolism,AMPK Signaling Pathway,Endocrine and metabolic diseases,Obesity,Cardiovascular,Lipids,Fatty Acids,CPT1A
    分子量
    86 kDa/88 kDa
    基因ID
    1374
    UniProt
    P50416
    途径
    AMPK Signaling, Regulation of Lipid Metabolism by PPARalpha, Feeding Behaviour, Monocarboxylic Acid Catabolic Process
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