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COPS2 抗体 (AA 1-310)

COPS2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6138877
发货至: 中国
  • 抗原 See all COPS2 抗体
    COPS2 (COP9 Constitutive Photomorphogenic Homolog Subunit 2 (Arabidopsis) (COPS2))
    抗原表位
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-310
    适用
    • 54
    • 46
    • 42
    • 10
    • 10
    • 7
    • 6
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    宿主
    • 51
    • 2
    • 1
    克隆类型
    • 52
    • 2
    多克隆
    标记
    • 25
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This COPS2 antibody is un-conjugated
    应用范围
    • 47
    • 19
    • 18
    • 13
    • 10
    • 7
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    序列
    MSDMEDDFMC DDEEDYDLEY SEDSNSEPNV DLENQYYNSK ALKEDDPKAA LSSFQKVLEL EGEKGEWGFK ALKQMIKINF KLTNFPEMMN RYKQLLTYIR SAVTRNYSEK SINSILDYIS TSKQMDLLQE FYETTLEALK DAKNDRLWFK TNTKLGKLYL EREEYGKLQK ILRQLHQSCQ TDDGEDDLKK GTQLLEIYAL EIQMYTAQKN NKKLKALYEQ SLHIKSAIPH PLIMGVIREC GGKMHLREGE FEKAHTDFFE AFKNYDESGS PRRTTCLKYL VLANMLMKSG INPFDSQEAK PYKNDPEILA
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-310 of human COPS2 (NP_004227.1).
    亚型
    IgG
    Top Product
    Discover our top product COPS2 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:100
    说明

    HIGH QUALITY

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    COPS2 (COP9 Constitutive Photomorphogenic Homolog Subunit 2 (Arabidopsis) (COPS2))
    别名
    COPS2 (COPS2 产品)
    别名
    COPS2 antibody, ALIEN antibody, CSN2 antibody, SGN2 antibody, TRIP15 antibody, wu:fc05f05 antibody, wu:fc06g10 antibody, wu:fc60f04 antibody, wu:fl94f12 antibody, zgc:86624 antibody, csn2 antibody, Tb03.48O8.600 antibody, Trip15 antibody, AI315723 antibody, C85265 antibody, Csn2 antibody, Sgn2 antibody, alien-like antibody, ATCSN2 antibody, CONSTITUTIVE PHOTOMORPHOGENIC 12 antibody, COP12 antibody, FUSCA 12 antibody, T20P8.4 antibody, T20P8_4 antibody, COP9 signalosome subunit 2 antibody, COP9 signalosome subunit 2 L homeolog antibody, COP9 signalosome complex subunit 2 antibody, COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis) antibody, proteasome family protein antibody, COPS2 antibody, cops2 antibody, cops2.L antibody, Tb927.3.2320 antibody, AOR_1_576084 antibody, PTRG_07106 antibody, LOC100283498 antibody, Cops2 antibody, csn-2 antibody, FUS12 antibody
    背景
    Essential component of the COP9 signalosome complex (CSN, a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively. Involved in early stage of neuronal differentiation via its interaction with NIF3L1.,COPS2,ALIEN,CSN2,SGN2,TRIP15,Epigenetics & Nuclear Signaling,Transcription Factors,Signal Transduction,COPS2
    分子量
    51 kDa/52 kDa
    基因ID
    9318
    UniProt
    P61201
    途径
    Cell Division Cycle
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