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CNOT1 抗体 (AA 2137-2376)

CNOT1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6138777
发货至: 中国
  • 抗原 See all CNOT1 抗体
    CNOT1 (CCR4-NOT Transcription Complex, Subunit 1 (CNOT1))
    抗原表位
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    AA 2137-2376
    适用
    • 16
    • 2
    • 1
    宿主
    • 15
    • 1
    克隆类型
    • 16
    多克隆
    标记
    • 9
    • 3
    • 2
    • 2
    This CNOT1 antibody is un-conjugated
    应用范围
    • 13
    • 6
    • 5
    • 2
    • 2
    Western Blotting (WB), Immunofluorescence (IF)
    序列
    PRNMRLPDPF TPNLKVDMLS EINIAPRILT NFTGVMPPQF KKDLDSYLKT RSPVTFLSDL RSNLQVSNEP GNRYNLQLIN ALVLYVGTQA IAHIHNKGST PSMSTITHSA HMDIFQNLAV DLDTEGRYLF LNAIANQLRY PNSHTHYFSC TMLYLFAEAN TEAIQEQITR VLLERLIVNR PHPWGLLITF IELIKNPAFK FWNHEFVHCA PEIEKLFQSV AQCCMGQKQA QQVMEGTGAS
    交叉反应
    人, 小鼠
    产品特性
    Polyclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 2137-2376 of human CNOT1 (NP_057368.3).
    亚型
    IgG
    Top Product
    Discover our top product CNOT1 Primary Antibody
  • 应用备注
    WB,1:200 - 1:2000,IF,1:50 - 1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    CNOT1 (CCR4-NOT Transcription Complex, Subunit 1 (CNOT1))
    别名
    CNOT1 (CNOT1 产品)
    别名
    CDC39 antibody, NOT1 antibody, NOT1H antibody, 6030411K04Rik antibody, AA815922 antibody, D830048B13 antibody, RGD1308009 antibody, GB18988 antibody, cdc39-like antibody, im:7141761 antibody, kiaa1007l antibody, wu:fc58h04 antibody, zgc:152902 antibody, CNOT1 antibody, not1 antibody, cdc39 antibody, not1h antibody, ad-005 antibody, NV18106 antibody, CCR4-NOT transcription complex subunit 1 antibody, CCR4-NOT transcription complex, subunit 1 antibody, CNOT1 antibody, Cnot1 antibody, LOC412371 antibody, cnot1 antibody, LOC100114396 antibody
    背景
    Scaffolding component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Its scaffolding function implies its interaction with the catalytic complex module and diverse RNA-binding proteins mediating the complex recruitment to selected mRNA 3'UTRs. Involved in degradation of AU-rich element (ARE-containing mRNAs probably via association with ZFP36. Mediates the recruitment of the CCR4-NOT complex to miRNA targets and to the RISC complex via association with TNRC6A, TNRC6B or TNRC6C. Acts as a transcriptional repressor. Represses the ligand-dependent transcriptional activation by nuclear receptors. Involved in the maintenance of embryonic stem (ES cell identity.,CNOT1,AD-005,CDC39,NOT1,NOT1H,Epigenetics & Nuclear Signaling,RNA Binding,CNOT1
    分子量
    173 kDa/241 kDa/266 kDa
    基因ID
    23019
    UniProt
    A5YKK6
    途径
    Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Stem Cell Maintenance
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