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Claudin 16 抗体 (AA 50-150)

CLDN16 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6138679
发货至: 中国
  • 抗原 See all Claudin 16 (CLDN16) 抗体
    Claudin 16 (CLDN16)
    抗原表位
    • 15
    • 8
    • 8
    • 7
    • 4
    • 2
    AA 50-150
    适用
    • 44
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 42
    • 2
    克隆类型
    • 43
    • 1
    多克隆
    标记
    • 14
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Claudin 16 antibody is un-conjugated
    应用范围
    • 21
    • 18
    • 14
    • 14
    • 13
    • 13
    • 6
    • 4
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    HLSGARAGVC PCCHPDGLLA TMRDLLQYIA CFFAFFSAGF LIVATWTDCW MVNADDSLEV STKCRGLWWE CVTNAFDGIR TCDEYDSILA EHPLKLVVTR A
    交叉反应
    人, 小鼠
    产品特性
    Polyclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    A synthetic peptide corresponding to a sequence within amino acids 50-150 of human CLDN16 (NP_006571.1).
    亚型
    IgG
    Top Product
    Discover our top product CLDN16 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    Claudin 16 (CLDN16)
    别名
    CLDN16 (CLDN16 产品)
    别名
    CLDN16 antibody, HOMG3 antibody, PCLN1 antibody, claudin-16 antibody, Pcln1 antibody, claudin 16 antibody, CLDN16 antibody, Cldn16 antibody
    背景
    Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is found primarily in the kidneys, specifically in the thick ascending limb of Henle, where it acts as either an intercellular pore or ion concentration sensor to regulate the paracellular resorption of magnesium ions. Defects in this gene are a cause of primary hypomagnesemia, which is characterized by massive renal magnesium wasting with hypomagnesemia and hypercalciuria, resulting in nephrocalcinosis and renal failure. This gene and the CLDN1 gene are clustered on chromosome 3q28.,CLDN16,HOMG3,PCLN1,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Tight Junctions,Cytoskeleton,CLDN16
    分子量
    33 kDa
    基因ID
    10686
    UniProt
    Q9Y5I7
    途径
    Hepatitis C
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