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Cyclin D1 抗体 (AA 96-295)

Name: Cyclin D1 抗体 (AA 96-295)
Brand: antibodies-online
SKU: ABIN6138079
Availability: OutOfStock

CCND1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

MBNL1-AS1 regulated the proliferation and apoptosis of BC cells via miR-135a/PHLPP2/FOXO1 axis. (Cyclin D1 抗体 (AA 96-295))

Immunohistochemistry of paraffin-embedded human esophagus using Cyclin D1 antibody (ABIN6127677, ABIN6138079, ABIN6138081 and ABIN6213800) at dilution of 1:100 (40x lens). (Cyclin D1 抗体 (AA 96-295))

IHC

Inhibition of MBNL1-AS1 promoted the tumorigenesis of BC cells through the regulation of miR-135a/PHLPP2/FOXO1 in vivo. (Cyclin D1 抗体 (AA 96-295))

Western blot analysis of extracts of rat kidney, using Cyclin D1 antibody (ABIN6127677, ABIN6138079, ABIN6138081 and ABIN6213800) at 1:1000 dilution. (Cyclin D1 抗体 (AA 96-295))

Immunohistochemistry of paraffin-embedded human liver cancer using Cyclin D1 antibody (ABIN6127677, ABIN6138079, ABIN6138081 and ABIN6213800) at dilution of 1:100 (40x lens). (Cyclin D1 抗体 (AA 96-295))

IHC

5 images

(1 reference)

产品编号 ABIN6138079

发货至: 中国

Datasheet as PDF

抗原 See all Cyclin D1 (CCND1) 抗体

Cyclin D1 (CCND1)
抗原表位
22

22

16

16

12

11

9

9

8

7

7

7

6

6

5

5

3

3

3

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 96-295
适用
234

126

121

40

20

18

16

12

10

9

4

3

3

3

3

2

2

1

1

1

1

1

1
人
宿主
202

54

1
兔
Compatible Secondaries
克隆类型
192

63
多克隆
标记
116

26

20

9

7

5

5

5

5

5

5

4

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1
This Cyclin D1 antibody is un-conjugated
应用范围
195

87

63

62

41

29

28

27

24

20

19

12

6

5

3

2

2

2

1

1

1
Western Blotting (WB), Immunohistochemistry (IHC)

序列

KSRLQLLGAT CMFVASKMKE TIPLTAEKLC IYTDNSIRPE ELLQMELLLV NKLKWNLAAM TPHDFIEHFL SKMPEAEENK QIIRKHAQTF VALCATDVKF ISNPPSMVAA GSVVAAVQGL NLRSPNNFLS YYRLTRFLSR VIKCDPDCLR ACQEQIEALL ESSLRQAQQN MDPKAAEEEE EEEEEVDLAC TPTDVRDVDI

交叉反应

人, 大鼠

产品特性

Polyclonal Antibodies

纯化方法

Affinity purification

免疫原

Recombinant fusion protein containing a sequence corresponding to amino acids 96-295 of human Cyclin D1 (NP_444284.1).

亚型

IgG

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CCND1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

应用备注

WB,1:500 - 1:1000,IHC,1:50 - 1:100

限制

仅限研究用
状态

Liquid

缓冲液

PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store at -20°C. Avoid freeze / thaw cycles.
Qin, Zheng, Zhou, Ou, Huang, Yan, Qin, Yang, Su, Bai, Guo, Lin: "Tsc1 deficiency impairs mammary development in mice by suppression of AKT, nuclear ERα, and cell-cycle-driving proteins." in: Scientific reports, Vol. 6, pp. 19587, (2017) (PubMed).
抗原

Cyclin D1 (CCND1)

别名

CCND1 (CCND1 产品)

别名

BCL1 antibody, D11S287E antibody, PRAD1 antibody, U21B31 antibody, AI327039 antibody, CycD1 antibody, Cyl-1 antibody, bcl-1 antibody, cD1 antibody, cb161 antibody, cycd1 antibody, etID37810.7 antibody, fb52e01 antibody, fc45c08 antibody, fc83a12 antibody, id:ibd1198 antibody, wu:fb52e01 antibody, wu:fc45c08 antibody, wu:fc83a12 antibody, ccnd1b antibody, prad1 antibody, ccnd1 antibody, ccnd1a antibody, bcl1 antibody, d11s287e antibody, u21b31 antibody, CCND1 antibody, cyclin D1 antibody, cyclin D1 S homeolog antibody, cyclin D1 L homeolog antibody, CCND1 antibody, Ccnd1 antibody, ccnd1 antibody, ccnd1.S antibody, ccnd1.L antibody

背景

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with tumor suppressor protein Rb and the expression of this gene is regulated positively by Rb. Mutations, amplification and overexpression of this gene, which alters cell cycle progression, are observed frequently in a variety of tumors and may contribute to tumorigenesis.,BCL1,D11S287E,PRAD1,U21B31,CCND1,Cyclin D1,cyclin D1,Epigenetics & Nuclear Signaling,Cancer,Signal Transduction,PI3K-Akt Signaling Pathway,Cell Biology & Developmental Biology,Cell Cycle,Cyclins,G1/S Checkpoint,Hedgehog Signaling Pathway,CCND1

分子量

33 kDa

基因ID

595

UniProt

P24385

途径

PI3K-Akt Signaling, Cell Division Cycle, Mitotic G1-G1/S Phases, ER-Nucleus Signaling