CBX6 抗体 (AA 80-180)
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- 抗原 See all CBX6 抗体
- CBX6 (Chromobox Homolog 6 (CBX6))
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抗原表位
- AA 80-180
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CBX6 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- LLKARAQAEA LRISDVHFSV KPSASASSPK LHSSAAVHRL KKDIRRCHRM SRRPLPRPDP QGGSPGLRPP ISPFSETVRI INRKVKPREP KRNRIILNLK V
- 交叉反应
- 人, 小鼠, 大鼠
- 产品特性
- Polyclonal Antibodies
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 80-180 of human CBX6 (NP_055107.3).
- 亚型
- IgG
- Top Product
- Discover our top product CBX6 Primary Antibody
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- 应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- CBX6 (Chromobox Homolog 6 (CBX6))
- 别名
- CBX6 (CBX6 产品)
- 别名
- cbx6 antibody, CBX6 antibody, zgc:101049 antibody, chromobox 6 antibody, chromobox 6 L homeolog antibody, chromobox homolog 6a antibody, cbx6 antibody, CBX6 antibody, Cbx6 antibody, cbx6.L antibody, cbx6a antibody
- 背景
- Component of a Polycomb group (PcG multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Possibly contributes to the target selectivity of the PRC1 complex by binding specific regions of chromatin. Recruitment to chromatin might occur in an H3K27me3-independent fashion (By similarity. May have a PRC1-independent function in embryonic stem cells (By similarity.,CBX6,Epigenetics & Nuclear Signaling,Chromatin Remodeling,CBX6
- 分子量
- 43 kDa
- 基因ID
- 23466
- UniProt
- O95503
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