CARD11 抗体 (AA 985-1154)
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- 抗原 See all CARD11 抗体
- CARD11 (Caspase Recruitment Domain Family, Member 11 (CARD11))
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抗原表位
- AA 985-1154
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CARD11 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF)
- 序列
- AKTLVQRLLN SGGAMEFTIC KSDIVTRDEF LRRQKTETII YSREKNPNAF ECIAPANIEA VAAKNKHCLL EAGIGCTRDL IKSNIYPIVL FIRVCEKNIK RFRKLLPRPE TEEEFLRVCR LKEKELEALP CLYATVEPDM WGSVEELLRV VKDKIGEEQR KTIWVDEDQL
- 交叉反应
- 人, 小鼠, 大鼠
- 产品特性
- Polyclonal Antibodies
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 985-1154 of human CARD11 (NP_115791.3).
- 亚型
- IgG
- Top Product
- Discover our top product CARD11 Primary Antibody
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- 应用备注
- WB,1:500 - 1:2000,IF,1:50 - 1:100
- 说明
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HIGH QUALITY
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- CARD11 (Caspase Recruitment Domain Family, Member 11 (CARD11))
- 别名
- CARD11 (CARD11 产品)
- 背景
- The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10.,CARD11,BENTA,BIMP3,CARMA1,IMD11,PPBL,Epigenetics & Nuclear Signaling,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Caspases,Immunology & Inflammation,B Cell Receptor Signaling Pathway,T Cell Receptor Signaling Pathway,CARD11
- 分子量
- 133 kDa
- 基因ID
- 84433
- UniProt
- Q9BXL7
- 途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, BCR Signaling
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