Calpain S1 抗体 (AA 69-268)
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- 抗原 See all Calpain S1 (CAPNS1) 抗体
- Calpain S1 (CAPNS1) (Calpain, Small Subunit 1 (CAPNS1))
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抗原表位
- AA 69-268
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Calpain S1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- 序列
- ISEAAAQYNP EPPPPRTHYS NIEANESEEV RQFRRLFAQL AGDDMEVSAT ELMNILNKVV TRHPDLKTDG FGIDTCRSMV AVMDSDTTGK LGFEEFKYLW NNIKRWQAIY KQFDTDRSGT ICSSELPGAF EAAGFHLNEH LYNMIIRRYS DESGNMDFDN FISCLVRLDA MFRAFKSLDK DGTGQIQVNI QEWLQLTMYS
- 交叉反应
- 人, 小鼠, 大鼠
- 产品特性
- Polyclonal Antibodies
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 69-268 of human Calpain small subunit 1 (NP_001740.1).
- 亚型
- IgG
- Top Product
- Discover our top product CAPNS1 Primary Antibody
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- 应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:100
- 说明
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HIGH QUALITY
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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Calpain and AR-V7: Two potential therapeutic targets to overcome acquired docetaxel resistance in castration-resistant prostate cancer cells." in: Oncology reports, Vol. 37, Issue 6, pp. 3651-3659, (2018) (PubMed).
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Calpain and AR-V7: Two potential therapeutic targets to overcome acquired docetaxel resistance in castration-resistant prostate cancer cells." in: Oncology reports, Vol. 37, Issue 6, pp. 3651-3659, (2018) (PubMed).
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- 抗原
- Calpain S1 (CAPNS1) (Calpain, Small Subunit 1 (CAPNS1))
- 别名
- CAPNS1 (CAPNS1 产品)
- 别名
- 30K antibody, CALPAIN4 antibody, CANP antibody, CANPS antibody, CAPN4 antibody, CDPS antibody, CSS1 antibody, Capn4 antibody, CAPNS1 antibody, Capa-4 antibody, Capa4 antibody, D7Ertd146e antibody, MGC84330 antibody, capns1 antibody, cb616 antibody, wu:fb81g08 antibody, wu:fl09e04 antibody, zgc:110603 antibody, calpain small subunit 1 antibody, calpain, small subunit 1 antibody, calpain, small subunit 1 L homeolog antibody, calpain, small subunit 1 a antibody, CAPNS1 antibody, Capns1 antibody, capns1.L antibody, capns1a antibody
- 背景
- This gene is a member of the calpain small subunit family. Calpains are calcium-dependent cysteine proteinases that are widely distributed in mammalian cells. Calpains operate as heterodimers, comprising a specific large catalytic subunit (calpain 1 subunit in Calpain I, and calpain 2 subunit in Calpain II), and a common small regulatory subunit encoded by this gene. This encoded protein is essential for the stability and function of both calpain heterodimers, whose proteolytic activities influence various cellular functions including apoptosis, proliferation, migration, adhesion, and autophagy. Calpains have been implicated in neurodegenerative processes, such as myotonic dystrophy. A pseudogene of this gene has been defined on chromosome 1. Alternative splicing results in multiple transcript variants.,CAPNS1,CALPAIN4,CANP,CANPS,CAPN4,CDPS,CSS1,Signal Transduction,Immunology & Inflammation,T Cell Receptor Signaling Pathway,Neuroscience,Calcium Signaling,CAPNS1
- 分子量
- 28 kDa
- 基因ID
- 826
- UniProt
- P04632
- 途径
- Apoptosis
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