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BCR 抗体 (AA 1-300)

BCR 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6137518
发货至: 中国
  • 抗原 See all BCR 抗体
    BCR (Breakpoint Cluster Region (BCR))
    抗原表位
    • 30
    • 16
    • 15
    • 7
    • 7
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-300
    适用
    • 115
    • 76
    • 33
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 108
    • 10
    • 4
    克隆类型
    • 112
    • 10
    多克隆
    标记
    • 57
    • 9
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This BCR antibody is un-conjugated
    应用范围
    • 66
    • 36
    • 36
    • 27
    • 26
    • 26
    • 19
    • 16
    • 10
    • 6
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    MVDPVGFAEA WKAQFPDSEP PRMELRSVGD IEQELERCKA SIRRLEQEVN QERFRMIYLQ TLLAKEKKSY DRQRWGFRRA AQAPDGASEP RASASRPQPA PADGADPPPA EEPEARPDGE GSPGKARPGT ARRPGAAASG ERDDRGPPAS VAALRSNFER IRKGHGQPGA DAEKPFYVNV EFHHERGLVK VNDKEVSDRI SSLGSQAMQM ERKKSQHGAG SSVGDASRPP YRGRSSESSC GVDGDYEDAE LNPRFLKDNL IDANGGSRPP WPPLEYQPYQ SIYVGGMMEG EGKGPLLRSQ
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human BCR (NP_004318.3).
    亚型
    IgG
    Top Product
    Discover our top product BCR Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IHC,1:50 - 1:100
    说明

    HIGH QUALITY

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    BCR (Breakpoint Cluster Region (BCR))
    别名
    BCR (BCR 产品)
    别名
    si:dkey-83d9.7 antibody, zK83D9.7 antibody, BCR antibody, ALL antibody, BCR1 antibody, CML antibody, D22S11 antibody, D22S662 antibody, PHL antibody, 5133400C09Rik antibody, AI561783 antibody, AI853148 antibody, mKIAA3017 antibody, breakpoint cluster region antibody, BCR, RhoGEF and GTPase activating protein antibody, bcr antibody, BCR antibody, Bcr antibody
    背景
    A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in patients with chronic myelogenous leukemia. The chromosome 22 breakpoint for this translocation is located within the BCR gene. The translocation produces a fusion protein which is encoded by sequence from both BCR and ABL, the gene at the chromosome 9 breakpoint. Although the BCR-ABL fusion protein has been extensively studied, the function of the normal BCR gene product is not clear. The protein has serine/threonine kinase activity and is a GTPase-activating protein for p21rac. Two transcript variants encoding different isoforms have been found for this gene.,BCR,ALL,BCR1,CML,D22S11,D22S662,PHL,Cancer,Signal Transduction,G protein signaling,Signal Transduction,Kinase,Serine/threonine kinases,PI3K-Akt Signaling Pathway,Immunology & Inflammation,B Cell Receptor Signaling Pathway,NF-kB Signaling Pathway,BCR
    分子量
    137 kDa/142 kDa
    基因ID
    613
    UniProt
    P11274
    途径
    Regulation of Leukocyte Mediated Immunity, Platelet-derived growth Factor Receptor Signaling
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