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- 抗原 See all AXIN2 抗体
- AXIN2 (Axin 2 (AXIN2))
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抗原表位
- AA 650-750
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This AXIN2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- 序列
- RSSPGERASR HHLWGGNSGH PRTTPRAHLF TQDPAMPPLT PPNTLAQLEE ACRRLAEVSK PPKQRCCVAS QQRDRNHSAT VQTGATPFSN PSLAPEDHKE P
- 交叉反应
- 人, 小鼠, 大鼠
- 产品特性
- Polyclonal Antibodies
- 纯化方法
- Affinity purification
- 免疫原
- A synthetic peptide corresponding to a sequence within amino acids 650-750 of human AXIN2 (NP_004646.3).
- 亚型
- IgG
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- 应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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Periostin activates pathways involved in epithelial-mesenchymal transition in adamantinomatous craniopharyngioma." in: Journal of the neurological sciences, Vol. 360, pp. 49-54, (2016) (PubMed).
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Periostin activates pathways involved in epithelial-mesenchymal transition in adamantinomatous craniopharyngioma." in: Journal of the neurological sciences, Vol. 360, pp. 49-54, (2016) (PubMed).
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- 抗原
- AXIN2 (Axin 2 (AXIN2))
- 别名
- AXIN2 (AXIN2 产品)
- 别名
- AXIL antibody, ODCRCS antibody, axil antibody, wu:fb37c08 antibody, zgc:111942 antibody, axin-2 antibody, xarp antibody, MGC81576 antibody, arp-A antibody, axin2 antibody, Axi1 antibody, Axil antibody, Conductin antibody, axin 2 antibody, axin 2 (conductin, axil) antibody, axin 2 (conductin, axil) S homeolog antibody, AXIN2 antibody, axin2 antibody, axin2.S antibody, Axin2 antibody
- 背景
- The Axin-related protein, Axin2, presumably plays an important role in the regulation of the stability of beta-catenin in the Wnt signaling pathway, like its rodent homologs, mouse conductin/rat axil. In mouse, conductin organizes a multiprotein complex of APC (adenomatous polyposis of the colon), beta-catenin, glycogen synthase kinase 3-beta, and conductin, which leads to the degradation of beta-catenin. Apparently, the deregulation of beta-catenin is an important event in the genesis of a number of malignancies. The AXIN2 gene has been mapped to 17q23-q24, a region that shows frequent loss of heterozygosity in breast cancer, neuroblastoma, and other tumors. Mutations in this gene have been associated with colorectal cancer with defective mismatch repair.,AXIN2,AXIL,ODCRCS,axin-2,Epigenetics & Nuclear Signaling,Cancer,Cell Biology & Developmental Biology,Cell Cycle,Centrosome,Cell differentiation,Wnt/β-Catenin Signaling Pathway,ESC Pluripotency and Differentiation,Neuroscience,Stem Cells,AXIN2
- 分子量
- 93 kDa
- 基因ID
- 8313
- UniProt
- Q9Y2T1
- 途径
- Regulation of G-Protein Coupled Receptor Protein Signaling
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