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AXIN2 抗体 (AA 650-750)

AXIN2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6137382
发货至: 中国
  • 抗原 See all AXIN2 抗体
    AXIN2 (Axin 2 (AXIN2))
    抗原表位
    • 15
    • 14
    • 11
    • 8
    • 7
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 650-750
    适用
    • 70
    • 53
    • 40
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    宿主
    • 83
    • 2
    克隆类型
    • 74
    • 11
    多克隆
    标记
    • 24
    • 8
    • 8
    • 7
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This AXIN2 antibody is un-conjugated
    应用范围
    • 62
    • 37
    • 30
    • 14
    • 13
    • 13
    • 6
    • 5
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    序列
    RSSPGERASR HHLWGGNSGH PRTTPRAHLF TQDPAMPPLT PPNTLAQLEE ACRRLAEVSK PPKQRCCVAS QQRDRNHSAT VQTGATPFSN PSLAPEDHKE P
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    A synthetic peptide corresponding to a sequence within amino acids 650-750 of human AXIN2 (NP_004646.3).
    亚型
    IgG
  • 应用备注
    WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • Chen, Zheng, Liu, Shi, Qi: "Periostin activates pathways involved in epithelial-mesenchymal transition in adamantinomatous craniopharyngioma." in: Journal of the neurological sciences, Vol. 360, pp. 49-54, (2016) (PubMed).

  • 抗原
    AXIN2 (Axin 2 (AXIN2))
    别名
    AXIN2 (AXIN2 产品)
    别名
    AXIL antibody, ODCRCS antibody, axil antibody, wu:fb37c08 antibody, zgc:111942 antibody, axin-2 antibody, xarp antibody, MGC81576 antibody, arp-A antibody, axin2 antibody, Axi1 antibody, Axil antibody, Conductin antibody, axin 2 antibody, axin 2 (conductin, axil) antibody, axin 2 (conductin, axil) S homeolog antibody, AXIN2 antibody, axin2 antibody, axin2.S antibody, Axin2 antibody
    背景
    The Axin-related protein, Axin2, presumably plays an important role in the regulation of the stability of beta-catenin in the Wnt signaling pathway, like its rodent homologs, mouse conductin/rat axil. In mouse, conductin organizes a multiprotein complex of APC (adenomatous polyposis of the colon), beta-catenin, glycogen synthase kinase 3-beta, and conductin, which leads to the degradation of beta-catenin. Apparently, the deregulation of beta-catenin is an important event in the genesis of a number of malignancies. The AXIN2 gene has been mapped to 17q23-q24, a region that shows frequent loss of heterozygosity in breast cancer, neuroblastoma, and other tumors. Mutations in this gene have been associated with colorectal cancer with defective mismatch repair.,AXIN2,AXIL,ODCRCS,axin-2,Epigenetics & Nuclear Signaling,Cancer,Cell Biology & Developmental Biology,Cell Cycle,Centrosome,Cell differentiation,Wnt/β-Catenin Signaling Pathway,ESC Pluripotency and Differentiation,Neuroscience,Stem Cells,AXIN2
    分子量
    93 kDa
    基因ID
    8313
    UniProt
    Q9Y2T1
    途径
    Regulation of G-Protein Coupled Receptor Protein Signaling
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