ATG14 抗体 (AA 1-310)
Quick Overview for ATG14 抗体 (AA 1-310) (ABIN6137246)
抗原
See all ATG14 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-310
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序列
- MASPSGKGAR ALEAPGCGPR PLARDLVDSV DDAEGLYVAV ERCPLCNTTR RRLTCAKCVQ SGDFVYFDGR DRERFIDKKE RLSRLKSKQE EFQKEVLKAM EGKWITDQLR WKIMSCKMRI EQLKQTICKG NEEMEKNSEG LLKTKEKNQK LYSRAQRHQE KKEKIQRHNR KLGDLVEKKT IDLRSHYERL ANLRRSHILE LTSVIFPIEE VKTGVRDPAD VSSESDSAMT SSTVSKLAEA RRTTYLSGRW VCDDHNGDTS ISITGPWISL PNNGDYSAYY SWVEEKKTTQ GPDMEQSNPA YTISAALCYA
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-310 of human ATG14 (NP_055739.2).
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亚型
- IgG
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anti-ATG14 Autophagy Related 14 (ATG14) (AA 43-303) antibody
ATG14 适用: 人 ELISA, IHC 宿主: 小鼠 Monoclonal 1F7C10 unconjugated
anti-ATG14 Autophagy Related 14 (ATG14) antibodyATG14 适用: 人, 大鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-ATG14 Autophagy Related 14 (ATG14) (AA 1-492) antibodyATG14 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-ATG14 Autophagy Related 14 (ATG14) (AA 70-101), (N-Term) antibodyATG14 适用: 人, 大鼠 WB, IHC, FACS, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-ATG14 Autophagy Related 14 (ATG14) (AA 1-310) antibodyATG14 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-ATG14 Autophagy Related 14 (ATG14) (AA 162-190) antibodyATG14 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB19671 unconjugated
anti-ATG14 Autophagy Related 14 (ATG14) (AA 55-84), (N-Term) antibodyATG14 适用: 人, 小鼠 WB, FACS 宿主: 兔 Polyclonal RB19669 unconjugated
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应用备注
- WB,1:500 - 1:2000,IF,1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- ATG14 (ATG14 Autophagy Related 14 (ATG14))
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别名
- ATG14
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背景
- Required for both basal and inducible autophagy. Determines the localization of the autophagy-specific PI3-kinase complex PI3KC3-C1. Plays a role in autophagosome formation and MAP1LC3/LC3 conjugation to phosphatidylethanolamine. Promotes BECN1 translocation from the trans-Golgi network to autophagosomes. Enhances PIK3C3 activity in a BECN1-dependent manner. Essential for the autophagy-dependent phosphorylation of BECN1. Stimulates the phosphorylation of BECN1, but suppresses the phosphorylation PIK3C3 by AMPK. Binds to STX17-SNAP29 binary t-SNARE complex on autophagosomes and primes it for VAMP8 interaction to promote autophagosome-endolysosome fusion. Modulates the hepatic lipid metabolism (By similarity.,ATG14,ATG14L,BARKOR,KIAA0831,Signal Transduction,Cell Biology & Developmental Biology,Autophagy,Endocrine & Metabolism,Mitochondrial metabolism,ATGs,ATG14
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分子量
- 42 kDa/55 kDa
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基因ID
- 22863
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UniProt
- Q6ZNE5
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途径
- Autophagy
抗原
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